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DeepHistone

DeepHistone is a deep learning method to discriminate whether a DNA fragment has modification of a certain histone marker, using DNA sequence and chromatin accessibility information.

Requirements

  • python 2.7/3.6
  • pytorch 0.4
  • numpy
  • pandas
  • sk-learn

Installation

Download DeepHistone by:

git clone https://github.com/QijinYin/DeepHistone

Installation has been tested in a Linux platform with python 2.7/3.6 .

Instructions

  1. data preprocessing
    demo dataset was generated and saved in npz format.
  2. model training and estimating

python train.py

Citation

  • Paper is in review.

License

This project is licensed under the MIT License - see the LICENSE.md file for details

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