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Nerve terminal currents at lizard neuromuscular junction (Lindgren, Moore 1989)
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Lindgren and Moore. (1989) Identification of ionic currents at presynaptic nerve terminal of the lizard. J. Physiol. 414: 201-222 Experimental observations of ionic currents localized in the presynaptic terminal region were made with a focal loose-patch clamp. In addition to finding Hodgkin-Huxley (HH) type sodium and potassium currents an L type calcium channel and a calcium-activated potassium channel were identified. Computer simulations matching the invasion of the action potential (figure 2) and the major current patterns (figure 1) were able to be generated, using only the Na and K channels of HH The NEURON implementation of this model was prepared by Michael Hines. Questions about details of this implementation should be addressed to him at michael.hines@yale.edu.
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Nerve terminal currents at lizard neuromuscular junction (Lindgren, Moore 1989)
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