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Figure 4

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Dose dependent degranulation

To quantify dose dependent degranulation a flow cytometry based CD107a assay was performed. CD107a surface expression serves as a marker for NK cell degranulation. PBMC were cultured with cells and 1615EpCAM133 TetraKE, EpCAM16 BiKE or 16133 BiKE at the labeled concentrations (n=3). P-values were estimated with one-way-ANOVA values are presented with standard deviation.

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