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Figure 4
Inflammatory infiltrate in eosinophil null mucosa is predominated by neutrophils. Whole colon flow cytometry analysis for infiltrating myeloid leucocytes in wild type (WT)-colons and PHIL-colons in dextran sodium sulfate (DSS)-colitis. Derivation and quantification of relative proportions of (A and B) neutrophils and eosinophils, (C and D) macrophage and (E and F) dendritic cell infiltrates comparing WT-DSS with PHIL-DSS-colitis. Data are expressed as means±SEM of seven individual mice per group and represent >3-independent experimental repeats following 6 days of colitis. **p≤0.01, Wild Type versus PHIL.
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