Table 2

Differences in FA between DS adults and similarly aged non-DS (CTL) participants

FA–group analysis-DS versus CTL

	Frontal	Parietal	Temporal	Occipital
Forceps-minor	2119	0	0	0
IFOF-R	1557	106	546	0
IFOF-R	1718	42	410	0
Uncinate-L	1342	59	125	0
Uncinate-R	1031	15	90	0
Genu-CC	175	0	0	0
Ant_Thal_Rad-L	1519	60	15	1
Ant_Thal_Rad-R	1124	0	4	0
SLF-L	657	1176	64	0
SLF-R	245	11	0	0
Cing_Cing Gyr-R	199	266	0	74
Cing_Cing Gyr-L	0	0	0	0
Body-CC	0	7	0	0
Cing_Hipp-L	0	0	0	0
Cing_Hipp-R	0	0	0	0
CS-L	8	118	0	0
CS-R	0	0	0	0
Splenium-CC	0	160	0	0
Forceps-major	0	7	0	0
ILF-L	0	92	473	39
ILF-R	0	0	259	0

Summary of 1 mm³ voxels within major white matter fiber tracks (corresponding to blue ROIs from Fig. 2). The number of voxels within each lobe of the brain is listed. Key: Ant_Thal_Rad, anterior thalamic radiations; CC, corpus callosum; Cing_Cing_-Gyr, cingulum of cingulate gyrus; Cing_Hipp, cingulum of hippocampus; CS, corticospinal; FA, fractional anisotropy; IFOF, inferior frontal occipital fasciculus; ILF, inferior longitudinal fasciculus; L, left; R, right; ROIs, regions of interest; SLF, superior longitudinal fasciculus.