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Figure 4

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cCFU-Fs Are Lost after Irradiation and Cannot Be Rescued by Whole BM Transplantation

(A) Overview of BM transplant experimental design. All transplants were on mice 8 weeks of age.

(B) Large colony formation was completely lost in BM transplanted mice. Colony formation was not rescued after 3 months or 6 months aging, or after MI.

(C) Reduced BM CFU-F colonies from BM-GFP chimeric mice, which do not recover after 6 months.

(D) Majority of remaining BM CFU-F colonies are GFP+, indicating donor origin.

Error bars = SEM between independent experiments. See also Figure S4.

Images in this article

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