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Deoxyguanosine diphosphate

Deoxyguanosine diphosphate (dGDP) is a nucleoside diphosphate. It is related to the common nucleic acid guanosine triphosphate (GTP), with the -OH group on the 2' carbon on the nucleotide's pentose removed (hence the deoxy- part of the name), and with one fewer phosphoryl group than GTP.[1]

Deoxyguanosine diphosphate
Skeletal formula of deoxyguanosine diphosphate
Space-filling model of the deoxyguanosine diphosphate anion
Names
IUPAC name
2′-Deoxyguanosine 5′-(trihydrogen diphosphate)
Systematic IUPAC name
[(2R,3S,5R)-5-(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl trihydrogen diphosphate
Other names
dGDP; 2'-Deoxyguanosine-5'-diphosphate; 2'-Deoxy-GDP; 5'-dGDP
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
  • InChI=1S/C10H15N5O10P2/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1 ☒N
    Key: CIKGWCTVFSRMJU-KVQBGUIXSA-N ☒N
  • InChI=1/C10H15N5O10P2/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17)/t4-,5+,6+/m0/s1
    Key: CIKGWCTVFSRMJU-KVQBGUIXBA
  • O=P(O)(O)OP(=O)(O)OC[C@H]3O[C@@H](n1cnc2c1NC(=N/C2=O)\N)C[C@@H]3O
Properties
C10H15N5O10P2
Molar mass 427.203 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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See also

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References

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  1. ^ "2'-Deoxyguanosine-5'-Diphosphate". DrugBank.