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Benzomorphan is a chemical compound that is the base for a series of drugs which variably act on the sigma receptors and κ-opioid receptors, including the following compounds:

Benzomorphan
Names
IUPAC name
6,7-Benzomorphan
Other names
  • 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine<
  • 10-Azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-triene
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2 ☒N
    Key: NSLKFRGZLUIUKO-UHFFFAOYSA-N ☒N
  • InChI=1/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2
    Key: NSLKFRGZLUIUKO-UHFFFAOYAF
  • C1CNC2CC1C3=CC=CC=C3C2
Properties
C12H15N
Molar mass 173.259 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Some of these agents are used as analgesics, including pentazocine, phenazocine, dezocine, and eptazocine.[1][2]

See also

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References

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  1. ^ Kar, Ashutosh (2005). Medicinal Chemistry - Google Books. ISBN 9788122415650.
  2. ^ Cittern PA, Kapoor VK, Parfitt RT (October 1986). "Preparation and analgesic activity of (−)-11 alpha-substituted 1,2,3,4,5,6-hexahydro-6 alpha,7-(methyleneoxy)-2,6-methano-3-benzazocines". Journal of Medicinal Chemistry. 29 (10): 1929–33. doi:10.1021/jm00160a022. PMID 2876100.