3-Hydroxybenzoate—CoA ligase (EC 6.2.1.37, 3-hydroxybenzoyl-CoA synthetase, 3-hydroxybenzoate-coenzyme A ligase (AMP-forming), 3-hydroxybenzoyl coenzyme A synthetase, 3-hydroxybenzoyl-CoA ligase) is an enzyme with systematic name 3-hydroxybenzoate:CoA ligase (AMP-forming).[1] This enzyme catalyses the following chemical reaction
| 3-Hydroxybenzoate—CoA ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.2.1.37 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- ATP + 3-hydroxybenzoate + CoA AMP + diphosphate + 3-hydroxybenzoyl-CoA
The enzyme works equally well with 4-hydroxybenzoate.
References
edit- ^ Laempe D, Jahn M, Breese K, Schägger H, Fuchs G (February 2001). "Anaerobic metabolism of 3-hydroxybenzoate by the denitrifying bacterium Thauera aromatica". Journal of Bacteriology. 183 (3): 968–79. doi:10.1128/jb.183.3.968-979.2001. PMC 94965. PMID 11208796.
External links
edit- 3-hydroxybenzoate—CoA+ligase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)