Tombusvirus is a genus of viruses, in the family Tombusviridae. Plants serve as natural hosts. There are 17 species in this genus. Symptoms associated with this genus include mosaic.[1][2] The name of the genus comes from Tomato bushy stunt virus.
| Tombusvirus | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Kitrinoviricota |
| Class: | Tolucaviricetes |
| Order: | Tolivirales |
| Family: | Tombusviridae |
| Subfamily: | Procedovirinae |
| Genus: | Tombusvirus |
Taxonomy
editThe genus contains the following species:[2]
- Artichoke mottled crinkle virus
- Carnation Italian ringspot virus
- Cucumber Bulgarian virus
- Cucumber necrosis virus
- Cymbidium ringspot virus
- Eggplant mottled crinkle virus
- Grapevine Algerian latent virus
- Havel River virus
- Lato River virus
- Limonium flower distortion virus
- Moroccan pepper virus
- Neckar River virus
- Pelargonium leaf curl virus
- Pelargonium necrotic spot virus
- Petunia asteroid mosaic virus
- Sikte waterborne virus
- Tomato bushy stunt virus
Structure
editViruses in Tombusvirus are non-enveloped, with icosahedral and spherical geometries, and T=3 symmetry. The diameter is around 28-34 nm. Genomes are linear and non-segmented, positive sense, single-stranded RNA, around 4-5.4kb in length.[1] These virions have a regular surface structure and are composed of 17% nucleic acid.
| Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
|---|---|---|---|---|---|
| Tombusvirus | Icosahedral | T=3 | Non-enveloped | Linear | Monopartite |
Life cycle
editViral replication is cytoplasmic, and is lysogenic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription, using the premature termination model of subgenomic RNA transcription is the method of transcription. Translation takes place by suppression of termination. The virus exits the host cell by tubule-guided viral movement. Plants serve as the natural host. Transmission routes are mechanical, seed borne, and contact.[1]
| Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
|---|---|---|---|---|---|---|---|
| Tombusvirus | Plants | None | Viral movement; mechanical inoculation | Viral movement | Cytoplasm | Cytoplasm | Mechanical: contact; seed |
The virus uses the cis-regulatory elements, Tombus virus defective interfering (DI) RNA region 3 and Tombusvirus 5' UTR to control expression of defective interfering RNAs and viral RNA replication.[3][4]
References
edit- ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
- ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 16 May 2021.
- ^ Ray D, White KA (2003). "An internally located RNA hairpin enhances replication of Tomato bushy stunt virus RNAs". J. Virol. 77 (1): 245–57. doi:10.1128/JVI.77.1.245-257.2003. PMC 140596. PMID 12477830.
- ^ Wu B, Vanti WB, White KA (2001). "An RNA domain within the 5' untranslated region of the tomato bushy stunt virus genome modulates viral RNA replication". J. Mol. Biol. 305 (4): 741–56. doi:10.1006/jmbi.2000.4298. PMID 11162089.