Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.[1]
| caspase 5, apoptosis-related cysteine peptidase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CASP5 | ||||||
| Alt. symbols | ICE(rel)III, ICH3 | ||||||
| NCBI gene | 838 | ||||||
| HGNC | 1506 | ||||||
| OMIM | 602665 | ||||||
| RefSeq | NM_004347 | ||||||
| UniProt | P51878 | ||||||
| Other data | |||||||
| EC number | 3.4.22.58 | ||||||
| Locus | Chr. 11 q22.2-q22.3 | ||||||
| |||||||
See also
editReferences
edit- ^ Martinon F, Tschopp J (2007). "Inflammatory caspases and inflammasomes: master switches of inflammation". Cell Death Differ. 14 (1): 10–22. doi:10.1038/sj.cdd.4402038. PMID 16977329.
External links
edit- The MEROPS online database for peptidases and their inhibitors: C14.008[permanent dead link]
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