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Diacetolol

From Wikipedia, the free encyclopedia
Diacetolol
Clinical data
Routes of
administration
Oral
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Elimination half-life8-13 hours
Identifiers
  • N-[3-acetyl-4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl]acetamide
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.040.974 Edit this at Wikidata
Chemical and physical data
FormulaC16H24N2O4
Molar mass308.378 g·mol−1
3D model (JSmol)
  • O=C(Nc1ccc(OCC(O)CNC(C)C)c(c1)C(=O)C)C
  • InChI=1S/C16H24N2O4/c1-10(2)17-8-14(21)9-22-16-6-5-13(18-12(4)20)7-15(16)11(3)19/h5-7,10,14,17,21H,8-9H2,1-4H3,(H,18,20) checkY
  • Key:AWOGXJOBNAWQSF-UHFFFAOYSA-N checkY
  (verify)

Diacetolol is the primary metabolite of acebutolol. It is a beta blocker and anti-arrhythmic agent.[1]

References

[edit]
  1. ^ Basil B, Jordan R (May 1982). "Pharmacological properties of diacetolol (M & B 16,942), a major metabolite of acebutolol". European Journal of Pharmacology. 80 (1): 47–56. doi:10.1016/0014-2999(82)90176-5. PMID 6124437.