- Sulfafurazole
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Sulfafurazole Systematic (IUPAC) name 4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide Clinical data AHFS/Drugs.com International Drug Names MedlinePlus a601049 Pregnancy cat. To be avoided within two months of term Legal status ℞ Prescription only Routes Oral Pharmacokinetic data Excretion Excreted unchanged in urine Identifiers CAS number 127-69-5 ATC code J01EB05 S01AB02 QJ01EQ05 PubChem CID 5344 DrugBank APRD00595 UNII 740T4C525W KEGG D00450 ChEMBL CHEMBL453 Chemical data Formula C11H13N3O3S Mol. mass 267.30 g/mol SMILES eMolecules & PubChem (what is this?) (verify) Sulphafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin or phenazopyridine. It is used locally in a 4% solution or ointment.
External links
- MeSH Sulfisoxazole
- MedlinePlus DrugInfo medmaster-a601049
- MedlinePlus DrugInfo medmaster-a601115
- DDB 30455
Antibacterials: nucleic acid inhibitors (J01E, J01M) Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)Sulfonamides
(DHPS inhibitor)Sulfaisodimidine • Sulfamethizole • Sulfadimidine • Sulfapyridine • Sulfafurazole • Sulfanilamide (Prontosil) • Sulfathiazole • SulfathioureaOther/ungroupedCombinationsTopoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)1st g.2nd g.Ciprofloxacin# • Enoxacin‡ • Fleroxacin‡ • Lomefloxacin • Nadifloxacin • Ofloxacin • Norfloxacin • Pefloxacin • Rufloxacin3rd g.4th g.Besifloxacin • Clinafloxacin† • Garenoxacin • Gemifloxacin • Moxifloxacin • Gatifloxacin‡ • Sitafloxacin • Trovafloxacin‡/Alatrofloxacin‡ • PrulifloxacinVet.Related (DG)Anaerobic DNA
inhibitorsNitrofuran derivativesRNA synthesis This systemic antibacterial-related article is a stub. You can help Wikipedia by expanding it.