Childhood obesity is considered one of the main public health concerns. Research in the field of obesity detection and prevention is moving towards promising solutions thanks to the use of Artificial Intelligence applied to data from cohorts of ...

Childhood obesity is a significant health concern impacting children and adolescents. The excess weight often initiates health issues such as diabetes, high blood pressure, and elevated cholesterol levels. Moreover, childhood obesity can contribute to ...

Observational studies have indicated a potential influence of childhood phenotypes on the later development of type 2 diabetes (T2D). However, the underlying biological mechanisms remain unclear. In this study, we conducted a comprehensive genome-...

• Childhood obesity, BMI, and SBP show significant genetic correlations with later-life T2D.
• Mediation analysis identifies potential mediators, such as extreme BMI, hip circumference, and waist circumference, influencing the link between ...

Obesity in children is related to the development of cardiometabolic complications later in life, where molecular changes of visceral adipose tissue (VAT) and skeletal muscle tissue (SMT) have been proven to be fundamental. The aim of this study ...

• Co-expression inter-tissue signatures of cardiometabolic risk are identified.
• Hub genes of identified co-expression clusters appears as promising biomarkers in obesity.
• MAPK route is involved in the metabolic regulation of adipose ...

Childhood obesity is a major public health challenge which is linked with the occurrence of diseases such as diabetes and cancer. The COVID-19 pandemic has forced changes to the lifestyle behaviors of children, thereby making the risk of ...

Childhood obesity is a multifactorial disease influencing the development of a range of metabolic disorders, where adipose tissue has been proved to be fundamental. The adipose tissue can be distributed throughout the body as visceral adipose ...

Childhood obesity is a major public health challenge. Early prediction and identification of the children at an elevated risk of developing childhood obesity may help in engaging earlier and more effective interventions to prevent and manage obesity. Most ...

The main objectives are (i) to study the relation of temperature of brown adipose tissue (BAT) with respect to obesity in different regions of the human body and to predict the most significant regional thermogram in determining the obese ...

Obesity is considered a global epidemic of the twenty-first century by the World Health Organization (WHO). Specifically, the Canary Islands has the highest level of this disease in Europe and 40% of children in Spain are overweight or obese. This ...

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• An agent-based model for studying noncommunicable diseases.
• A reasoning ...

This paper aims to test and illustrate the utility and extensibility of an existing model, SimNCD (Simulation of NonCommunicable Diseases). It also proposes a way to include questionnaires – widely used in epidemiology – in the ...

In this paper we present a finite-time 3-5 years old childhood obesity model to study the evolution of obesity in the next years in the Spanish region of Valencia. After a statistical study, it can be seen that sociocultural characteristics determine ...