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TEST-Net: transformer-enhanced Spatio-temporal network for infectious disease prediction

Published: 08 October 2024 Publication History

Abstract

Outbreaks of infectious diseases have caused tremendous human suffering and incalculable economic losses, and infectious diseases are a global public health problem that threatens human society. Therefore, it is necessary to model the spatial and temporal distribution characteristics of infectious diseases, explore the transmission trend of infectious diseases, establish an infection early warning model and take corresponding preventive and control measures, which can make the prevention and control work more targeted and forward-looking. Given the complex spatial correlation and temporal variation of infectious diseases, deep learning-based Spatio-temporal sequence prediction is widely employed because of its superior performance in capturing Spatio-temporal features. However, current deep learning-based infectious disease prediction methods utilize an encoder-decoder structure that provides barely satisfactory accuracy due to a lack of understanding of infectious disease prevalence factors or deficiencies in capturing representative Spatio-temporal patterns. In this paper, we develop the Transformer-Enhanced Spatio-temporal Network (TEST-Net) which consists of a temporal location coding module and a Spatio-temporal feature fusion module for Infectious disease prediction. Temporal information is input in TEST-Net by Temporal Location Encoding (TLE), and temporal and spatial correlation of sequences is extracted by a transformer-based attention network, and temporal features are fused with spatial features by a Spatio-temporal feature fusion network. Compared with other state-of-the-art methods, qualitative and quantitative results show that TSET-Net has an excellent performance in modeling the spatial and temporal distribution characteristics of data and performs well in the accuracy of long-term prediction of infectious disease.

References

[1]
Shen Y, Yuan K, Chen D, Colloc J, Yang M, Li Y, and Lei K An ontology-driven clinical decision support system (iddap) for infectious disease diagnosis and antibiotic prescription Artif. Intell. Med. 2018 86 20-32
[2]
Prilutsky D, Rogachev B, Marks RS, Lobel L, and Last M Classification of infectious diseases based on chemiluminescent signatures of phagocytes in whole blood Artif. Intell. Med. 2011 52 3 153-163
[3]
Silva JC, Shah SC, Rumoro DP, Bayram JD, Hallock MM, Gibbs GS, and Waddell MJ Comparing the accuracy of syndrome surveillance systems in detecting influenza-like illness: Guardian vs. rods vs. electronic medical record reports Artif. Intell. Med. 2013 59 3 169-174
[4]
Lucas PJ, de Bruijn NC, Schurink K, and Hoepelman A A probabilistic and decision-theoretic approach to the management of infectious disease at the icu Artif. Intell. Med. 2000 19 3 251-279
[5]
Iglesias N, Juarez JM, and Campos M Comprehensive analysis of rule formalisms to represent clinical guidelines: Selection criteria and case study on antibiotic clinical guidelines Artif. Intell. Med. 2020 103
[6]
Zamiri A, Yazdi HS, and Goli SA Temporal and spatial monitoring and prediction of epidemic outbreaks IEEE J. Biomed. Health Inform. 2014 19 2 735-744
[7]
Damone, A., Vainieri, M., Brunetto, M., Bonino, F., Nuti, S., Ciuti, G.: Decision-making algorithm and predictive model to assess the impact of infectious disease epidemics on the healthcare system: the covid-19 case study in italy, IEEE J. Biomed. Health Inform
[8]
Sun Z, Sun Z, Dong W, Shi J, and Huang Z Towards predictive analysis on disease progression: a variational hawkes process model IEEE J. Biomed. Health Inform. 2021 25 11 4195-4206
[9]
Agor JK, Paramita NLPS, and Özaltın OY Prediction of sepsis related mortality: an optimization approach IEEE J. Biomed. Health Inform. 2021 25 11 4207-4216
[10]
Wang Z and Yao B Multi-branching temporal convolutional network for sepsis prediction IEEE J. Biomed. Health Inform. 2021 26 2 876-887
[11]
Kermack WO and McKendrick AG Contributions to the mathematical theory of epidemics-i. 1927 Bull. Math. Biol. 1991 53 1–2 33-55
[12]
Perelson AS, Neumann AU, Markowitz M, Leonard JM, and Ho DD Hiv-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time Science 1996 271 5255 1582-1586
[13]
Dye C and Gay N Modeling the sars epidemic Science 2003 300 5627 1884-1885
[14]
Gandon S, Day T, Metcalf CJE, and Grenfell BT Forecasting epidemiological and evolutionary dynamics of infectious diseases Trends Ecol. Evol. 2016 31 10 776-788
[15]
Grassly NC and Fraser C Mathematical models of infectious disease transmission Nat. Rev. Microbiol. 2008 6 6 477-487
[16]
SUN, B., HE, S.-z.: Application of the grey system residual error model and grey verhulst model on forecasting malignant tumor death, J. Preven. Med. Inf
[17]
Liang, W. Y. L. W.-d., Jing, Q. H. J.-l. A., Yuan, L.: Analyzing and forecasting to epidemic tendency of pulmonary tuberculosis in jiangsu province, Jiangsu Health Care
[18]
Bates JM and Granger CW The combination of forecasts J. Oper. Res. Soc. 1969 20 4 451-468
[19]
Uys PW, van Helden PD, and Hargrove JW Tuberculosis reinfection rate as a proportion of total infection rate correlates with the logarithm of the incidence rate: a mathematical model J. R. Soc. Interface 2009 6 30 11-15
[20]
Übeylı ED and Güler I Spectral analysis of internal carotid arterial doppler signals using fft, ar, ma, and arma methods Comput. Biol. Med. 2004 34 4 293-306
[21]
Chen K, Zhang L-B, Liu J-S, Gao Y, Wu Z, Zhu H-C, Du C-P, Mai X-L, Yang C-F, and Chen Y Robust restoration of low-dose cerebral perfusion ct images using ncs-unet Nucl. Sci. Tech. 2022 33 3 1-15
[22]
Karimi D, Warfield SK, and Gholipour A Transfer learning in medical image segmentation: new insights from analysis of the dynamics of model parameters and learned representations Artif. Intell. Med. 2021 116
[23]
Talo M Automated classification of histopathology images using transfer learning Artif. Intell. Med. 2019 101
[24]
Chen L, Yang X, Jeon G, Anisetti M, and Liu K A trusted medical image super-resolution method based on feedback adaptive weighted dense network Artif. Intell. Med. 2020 106
[25]
Conze P-H, Kavur AE, Cornec-Le Gall E, Gezer NS, Le Meur Y, Selver MA, and Rousseau F Abdominal multi-organ segmentation with cascaded convolutional and adversarial deep networks Artif. Intell. Med. 2021 117
[26]
Ismael SAA, Mohammed A, and Hefny H An enhanced deep learning approach for brain cancer MRI images classification using residual networks Artif. Intell. Med. 2020 102
[27]
Zhang Y, Lv T, Ge R, Zhao Q, Hu D, Zhang L, Liu J, Zhang Y, Liu Q, Zhao W, et al. Cd-net: comprehensive domain network with spectral complementary for dect sparse-view reconstruction IEEE Trans. Comput. Imaging 2021 7 436-447
[28]
Tseng F-M, Yu H-C, and Tzeng G-H Combining neural network model with seasonal time series arima model Technol. Forecast. Soc. Chang. 2002 69 1 71-87
[29]
Hyndman, R. J., Athanasopoulos, G.: Forecasting: principles and practice, OTexts, (2018)
[30]
Pfeifer PE and Deutrch SJ A three-stage iterative procedure for space-time modeling phillip Technometrics 1980 22 1 35-47
[31]
Box, G.E., Jenkins, G.M., Reinsel, G.C., Ljung, G.M.: Time series analysis: forecasting and control, John Wiley & Sons, (2015)
[32]
Das, M., Ghosh, S. K.: A probabilistic approach for weather forecast using spatio-temporal inter-relationships among climate variables, in: 2014 9th International Conference on Industrial and Information Systems (ICIIS), IEEE, pp. 1–6 (2014)
[33]
Zhang, Y., Roughan, M., Willinger, W., Qiu, L.: Spatio-temporal compressive sensing and internet traffic matrices, in: Proceedings of the ACM SIGCOMM 2009 conference on Data communication, pp. 267–278 (2009)
[34]
Das M and Ghosh SK sembnet: a semantic bayesian network for multivariate prediction of meteorological time series data Pattern Recogn. Lett. 2017 93 192-201
[35]
Zaremba, W., Sutskever, I., Vinyals, O.: Recurrent neural network regularization, arXiv preprint arXiv:1409.2329
[36]
Gers FA and Schmidhuber E Lstm recurrent networks learn simple context-free and context-sensitive languages IEEE Trans. Neural Netw. 2001 12 6 1333-1340
[37]
Cho, K., Van Merriënboer, B., Gulcehre, C., Bahdanau, D., Bougares, F., Schwenk, H., Bengio, Y.: Learning phrase representations using rnn encoder-decoder for statistical machine translation, arXiv preprint arXiv:1406.1078
[38]
Wu, Y., Tan, H.: Short-term traffic flow forecasting with spatial-temporal correlation in a hybrid deep learning framework, arXiv preprint arXiv:1612.01022
[39]
Zhao Q, Yang M, Cheng Z, Li Y, and Wang J Biomedical data and deep learning computational models for predicting compound-protein relations IEEE/ACM Trans. Comput. Biol. Bioinf. 2021 19 4 2092-2110
[40]
Spencer M, Eickholt J, and Cheng J A deep learning network approach to ab initio protein secondary structure prediction IEEE/ACM Trans. Comput. Biol. Bioinf. 2014 12 1 103-112
[41]
Sharma, A., Kumar, R., Semwal, R., Aier, I., Tyagi, P., Varadwaj, P.: Deepolf: deep neural network based architecture for predicting odorants and their interacting olfactory receptors, IEEE/ACM Trans. Comput. Biol. Bioinf.
[42]
Liu, S., Zhang, Y., Cui, Y., Qiu, Y., Deng, Y., Zhang, Z. M., Zhang, W.: Enhancing drug-drug interaction prediction using deep attention neural networks, IEEE/ACM Trans. Comput. Biol. Bioinf.
[43]
Chen, J., Li, K., Herrero, P., Zhu, T., Georgiou, P.: Dilated recurrent neural network for short-time prediction of glucose concentration., in: KHD@ IJCAI, pp. 69–73 (2018)
[44]
Chen, W., Wang, S., Long, G., Yao, L., Sheng, Q. Z., Li, X.: Dynamic illness severity prediction via multi-task rnns for intensive care unit, in: 2018 IEEE International Conference on Data Mining (ICDM), IEEE, pp. 917–922 (2018)
[45]
Zerveas, G., Jayaraman, S., Patel, D., Bhamidipaty, A., Eickhoff, C.: A transformer-based framework for multivariate time series representation learning, in: Proceedings of the 27th ACM SIGKDD Conference on Knowledge Discovery & Data Mining, pp. 2114–2124 (2021)
[46]
Vaswani, A., Shazeer, N., Parmar, N., Uszkoreit, J., Jones, L., Gomez, A. N., Kaiser, Ł., Polosukhin, I.: Attention is all you need, Advances in neural information processing systems 30
[47]
Baranyi, P.: Hfmd dataset, https://ivdc.chinacdc.cn/
[48]
Shi, X., Chen, Z., Wang, H., Yeung, D.-Y., Wong, W.-K., Woo, W.-c.: Convolutional lstm network: A machine learning approach for precipitation nowcasting, Advances in neural information processing systems 28
[49]
Shi, X., Gao, Z., Lausen, L., Wang, H., Yeung, D.-Y., Wong, W.-k., Woo, W.-c.: Deep learning for precipitation nowcasting: a benchmark and a new model, Advances in neural information processing systems 30
[50]
Hao, H., Wang, Y., Xia, Y., Zhao, J., Shen, F.: Temporal convolutional attention-based network for sequence modeling, arXiv preprint arXiv:2002.12530
[51]
Wang, X., Zhou, T., Wen, Q., Gao, J., Ding, B., Jin, R.: Card: Channel aligned robust blend transformer for time series forecasting, in: The Twelfth International Conference on Learning Representations, (2023)
[52]
Liang, D., Zhang, H., Yuan, D., Zhang, B., Zhang, M.: Minusformer: Improving time series forecasting by progressively learning residuals, arXiv preprint arXiv:2402.02332

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          Information & Contributors

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          Published In

          cover image Multimedia Systems
          Multimedia Systems  Volume 30, Issue 6
          Dec 2024
          413 pages

          Publisher

          Springer-Verlag

          Berlin, Heidelberg

          Publication History

          Published: 08 October 2024
          Accepted: 06 September 2024
          Received: 21 December 2023

          Author Tags

          1. Public health
          2. Infectious disease prediction
          3. Spatio-temporal sequence
          4. Deep learning
          5. Transformer

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          • Research-article

          Funding Sources

          • the State’s Key Project of Research and Development Plan
          • the Key Technologies Research and Development Program from the Ministry of Science and Technology
          • the National Natural Science Foundation
          • the National Key Research and Development Program of China

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