Elaboration and physicochemical behaviour of nano hydroxyapatite: silver nanoparticles biocompsite after "In vitro" assays
Abstract
Silver nanoparticles induce many beneficiate effects in biomedical materials when it is used in good dose. Silver is generally recognized by its inhibitory effect towards many bacterial strains and microorganisms commonly present in medical and industrial processes. In this work, hydroxyapatite/polyvinylpyrrolidone was doped with 2 different concentrations of silver nanoparticles prepared by reduction method.
Physicochemical characterization of compounds was carried out by using TEM, SEM and XRD methods. They permit to highlight the structural and morphological behavior of nano biomaterials after addition of Silver. The chemical reactivity and kinetic of bioactivity were studied. Ionic exchanges between compounds and SBF were achieved by using ICP-OES method. It is demonstrated that silver doped nanohydroxyapatite obviously improve the bioactivity of the apatite at the early stages of immersion. Hydroxyapatite was elaborated in the presence of polyvinylpyrrolidone (HA/PVP).
Obtained results show that the particles seemed to be like fibers with at least more than 100 nm in length and 10-20 nm in diameter.
After the "in vitro" assays, the releasing of Ca and P in silver-HA/PVP (Ag-HAP 1.5) and in silver-HA/PVP (Ag-HAP 5) is slower than that in HA/PVP (HAP). The presence of silver in the matrix slows the bioactivity and the chemical reactivity.
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Published In
August 2011
470 pages
ISBN:9781618040282
Publisher
World Scientific and Engineering Academy and Society (WSEAS)
Stevens Point, Wisconsin, United States
Publication History
Published: 23 August 2011
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