CAD/CAM milled complete removable dental prostheses: An <i>in vitro</i> evaluation of biocompatibility, mechanical properties, and surface roughness

Original Paper

CAD/CAM milled complete removable dental prostheses: An in vitro evaluation of biocompatibility, mechanical properties, and surface roughness

Murali SRINIVASAN, Harald GJENGEDAL, Maria CATTANI-LORENTE, Mira MOUSSA, Stéphane DURUAL, Division of Gerodontology, School of Dental Medicine, University of Bern">Martin SCHIMMEL, Service of Geriatrics, Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals of Geneva">Frauke MÜLLER

Author information

Murali SRINIVASAN
Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva
Harald GJENGEDAL
Department of Clinical Dentistry, University of Bergen
Maria CATTANI-LORENTE
Department of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva
Mira MOUSSA
Department of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva
Stéphane DURUAL
Department of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva
Martin SCHIMMEL
Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva
Division of Gerodontology, School of Dental Medicine, University of Bern
Frauke MÜLLER
Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva
Service of Geriatrics, Department of Internal Medicine, Rehabilitation and Geriatrics, University Hospitals of Geneva

Keywords: CAD/CAM milled complete removable dental prostheses, Complete dentures, CAD/CAM, Laser profilometry

JOURNAL FREE ACCESS

2018 Volume 37 Issue 4 Pages 526-533

DOI https://doi.org/10.4012/dmj.2017-207

Browse “Advance online publication” version

Details

Abstract

This study compared the biocompatibility, mechanical properties, and surface roughness of a pre-polymerized polymethyl methacrylate (PMMA) resin for CAD/CAM complete removable dental prostheses (CRDPs) and a traditional heat-polymerized PMMA resin. Two groups of resin substrates [Control (RC): conventional PMMA; Test (RA): CAD/CAM PMMA] were fabricated. Human primary osteoblasts and mouse embryonic-fibroblasts were cultured for biocompatibility assays. Mechanical properties and surface roughness were compared. ANOVA revealed no difference between the resin groups in the biocompatibility assays. RA demonstrated a higher elastic modulus (p=0.002), young’s modulus (p=0.002), plastic energy (p=0.002), ultimate strength (p=0.0004), yield point (p=0.016), strain at yield point (p=0.037), and toughness (p<0.0001); while RC displayed a higher elastic energy (p<0.0001). Laser profilometry concluded a rougher surface profile (p<0.0001) for RA. This study concluded that the tested CAD/CAM resin was equally biocompatible and presented with improved mechanical properties than the traditional heat-polymerized PMMA resin used in the fabrication of CRDPs.

Corresponding author

Register with J-STAGE for free!