Title:Case-based reasoning approach for diagnostic screening of children with developmental delays

Abstract:According to the World Health Organization, the population of children with developmental delays constitutes approximately 6% to 9% of the total population. Based on the number of newborns in Huaibei, Anhui Province, China, in 2023 (94,420), it is estimated that there are about 7,500 cases (suspected cases of developmental delays) of suspicious cases annually. Early identification and appropriate early intervention for these children can significantly reduce the wastage of medical resources and societal costs. International research indicates that the optimal period for intervention in children with developmental delays is before the age of six, with the golden treatment period being before three and a half years of age. Studies have shown that children with developmental delays who receive early intervention exhibit significant improvement in symptoms; some may even fully recover. This research adopts a hybrid model combining a CNN-Transformer model with Case-Based Reasoning (CBR) to enhance the screening efficiency for children with developmental delays. The CNN-Transformer model is an excellent model for image feature extraction and recognition, effectively identifying features in bone age images to determine bone age. CBR is a technique for solving problems based on similar cases; it solves current problems based on past experiences, similar to how humans solve problems through learning from experience. Given CBR's memory capability to judge and compare new cases based on previously stored old cases, it is suitable for application in support systems with latent and variable characteristics. Therefore, this study utilizes the CNN-Transformer-CBR to establish a screening system for children with developmental delays, aiming to improve screening efficiency.