Optimal cut-off for neutrophil-to-lymphocyte ratio: Fact or Fantasy? A prospective cohort study in metastatic cancer patients
Fig 3
Subgroup analysis illustrating the impact of the choice of neutrophil-to-lymphocyte ratio (NLR) cut-off value; examples with NLR ≥3.0 (A) and NLR ≥4.0 (B). The model was adjusted for age, sex, disease site and European Co-operative Oncology Group performance status, and the interaction test remained statistically non-significant across the different subgroups, irrespective of the cut-off value, in favour of a persisting negative effect of a high NLR value on prognosis. *Likelihood-ratio txt for interaction of term with NLR cut-off = 3.