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Modelling novelty detection in the thalamocortical loop

Fig 11

Dependence of deviance-detecting effect and thalamic response patterns on the cortico-thalamic and intra-thalamic connection strength.

(A) Three late oscillation patterns (regimes) of thalamocortical cells can be elicited by a whisker deflection (marked in red under the time axis). (B-D) Sensitivity of SSA and true deviance detection in L4, L6 and thalamus to the strength of cortico-thalamic coupling on RE cells, , given different TC-to-RE synaptic conductances, . Background colors denote one of the three regimes depicted in (A). (E) Analogous to (B-D), but by changing TC-to-RE synaptic conductances, , with cortico-thalamic coupling strength, , fixed. The starred value denotes the parameter’s default value.

Fig 11

doi: https://doi.org/10.1371/journal.pcbi.1009616.g011