Optimising efficacy of antibiotics against systemic infection by varying dosage quantities and times
Fig 2
Comparison of mathematical model and experimental results for survival rates for different ‘fixed dose’ treatments, with 0.9 mg either administered as a single dose, or split equally over 2 days, or split equally over 3 days: (A) 0.9 mg administered at 2 h; (B) 0.45 mg administered at 2 h and at 24 h; (C) 0.3 mg administered at 2 h, 24 h and 48 h. n = 45 for biological experiments; n = 5000 for mathematical model.