Heterogeneity and Convergence of Olfactory First-Order Neurons Account for the High Speed and Sensitivity of Second-Order Neurons
Figure 5
Firing rates and latencies at single pheromone doses are normally distributed with standard deviations related to means.
(A) Empirical CDFs of firing rates F (corrected from control stimulations) for ORN significant responses (staircases) from C = −1 (left) to 4 log ng (right) and fitted Gaussian distributions (dashed lines) of means Fμ and standard deviations σTr. (B) Same as (A) for ORN latencies. (C) Same as (A) for PNfiring rates. (D) Same as (A) for PN latencies. (E) Response heterogeneity plot of σTr versus Fμ as determined in (A) for ORNs (blue dots) and in (C) for PNs (red dots), with regression lines σTr ≈0.331 Fμ AP/s for C = −1 to 1 log ng (ORNs, dose indicated in blue) and −3 to −1 (PNs, in red) and σTr ≈35 AP/s for C>1 (ORNs) and> −1 (PNs). (F) Response heterogeneity plot of σTr versus Lμ for ORNs (blue) and PNs (red) based on (B, D).