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Research LetterIn-Press PreviewCardiologyGenetics
Open Access | 10.1172/JCI180670
Single-nuclei transcriptomics reveals TBX5-dependent targets in a patient with Holt-Oram syndrome
Jeffrey D. Steimle,1 Yi Zhao,2 Fansen Meng,2 Mikaela E. Taylor,1 Diwakar Turaga,3 Iki Adachi,4 Xiao Li,2 and James F. Martin1
1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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Li, X.
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1Department of Integrative Physiology, Baylor College of Medicine, Houston, United States of America
2McGill Gene Editing Laboratory, Texas Heart Institute, Houston, United States of America
3Department of Pediatrics, Baylor College of Medicine, Houston, United States of America
4Department of Surgery, Baylor College of Medicine, Houston, United States of America
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Martin, J.
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Published November 14, 2024 - More info
Copyright © 2024, Steimle et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Copyright © 2024 American Society for Clinical Investigation
ISSN: 0021-9738 (print), 1558-8238 (online)