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Electric Field Simulation for Tumor Treating Fields Using FEM: An Open Source and Easy-To-Use Implementation

Published: 28 September 2023 Publication History

Abstract

Tumor Treating Fields (TTFields) therapy is a promising cancer treatment technique that inhibits tumor cell proliferation by applying alternating electric fields. Numerical simulations of TTFields electric fields based on realistic models have been widely used to analyze and optimize treatment implementation. However, most simulations are limited by solving tools, require laborious pre-processing of the model, and can only be performed manually. The paper presents a new implementation for simulating the electric field distribution of TTFields based on an open-source finite element solver. The reliability of the new implementation was verified by comparing with the analytical solution of a simple cylindrical model. Then, compared with the common simulation scheme on a realistic head model, the practical significance of this implementation in simulating TTFields electric field distribution was evaluated. This implementation reduces the workload of pre-processing and provides convenience for building an automated workflow for TTFields modeling.

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    ICBIP '23: Proceedings of the 2023 8th International Conference on Biomedical Signal and Image Processing
    July 2023
    140 pages
    ISBN:9798400707698
    DOI:10.1145/3613307
    Permission to make digital or hard copies of all or part of this work for personal or classroom use is granted without fee provided that copies are not made or distributed for profit or commercial advantage and that copies bear this notice and the full citation on the first page. Copyrights for components of this work owned by others than the author(s) must be honored. Abstracting with credit is permitted. To copy otherwise, or republish, to post on servers or to redistribute to lists, requires prior specific permission and/or a fee. Request permissions from [email protected].

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    Published: 28 September 2023

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    Author Tags

    1. Tumor Treating Fields
    2. finite element method
    3. numerical simulation

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