TopPIC Gateway: A Web Gateway for Top-Down Mass Spectrometry Data Interpretation
Authors: 
In Kwon Choi, Eroma Abeysinghe, 
Eric Coulter, 
Suresh Marru, Marlon Pierce, Xiaowen LiuAuthors Info & Claims
Pages 461 - 464
Abstract
Top-down mass spectrometry-based proteomics has become the method of choice for identifying and quantifying intact proteoforms in biological samples. We present a web-based gateway for TopPIC suite, a widely used software suite consisting of four software tools for top-down mass spectrometry data interpretation: TopFD, TopPIC, TopMG, and TopDiff. The gateway enables the community to use heterogeneous collection of computing resources that includes high performance computing clusters at Indiana University and virtual clusters on XSEDE’s Jetstream Cloud resource for top-down mass spectral data analysis using TopPIC suite. The gateway will be a useful resource for proteomics researchers and students who have limited access to high-performance computing resources or who are not familiar with interacting with server-side supercomputers.
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Published In
July 2020
556 pages
ISBN:9781450366892
DOI:10.1145/3311790
Copyright © 2020 ACM.
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Published: 26 July 2020
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- Short-paper
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- Refereed limited
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- National Science Fundation
- National Institutes of Health
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PEARC '20: Practice and Experience in Advanced Research Computing
July 26 - 30, 2020
OR, Portland, USA
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Overall Acceptance Rate 133 of 202 submissions, 66%
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