Abstract
Identifying transient and nonpersistent abnormal electrocardiogram (ECG) waveforms by continuously monitoring the high-risk populations is of great importance for the diagnosis, treatment, and prevention of cardiovascular diseases. In recent years, fabric electrodes have been widely used in wearable devices because of their non-irritating properties and better comfort than traditional AgCl electrodes. However, the motion noise caused by the relative movement between the fabric electrodes and skin affects the quality of ECGs and reduces the accuracy of diagnosis. Therefore, delineating the ECG waveforms that are recorded from wearable devices with varying levels of noise is still challenging. In this study, a signal quality assessment (SQA)–based ECG waveform delineation method that is used for wearable systems was developed. The ECG signal was first preprocessed by a bandpass filter. Five indices, including the multiscale nonlinear amplitude statistical distribution (adSQI1, adSQI2), the proportion of energy-related to T wave (ptSQI), and heart rates computed from R waves and T waves (rHR and tHR, respectively), were then calculated from the preprocessed ECG signal. The signals were classified as good, acceptable, and unacceptable ECGs by combining these indices through the use of a neural network. Subsequently, the R waves or/and T waves were identified for the corresponding feature interpretations based on the SQA results. ECGs that were recorded from the chest belts from 29 volunteers at different activity statuses were divided into 4-s segments. A total of 7133 manually labeled segments were used to derive (4985 segments) and validate (2148 segments) the algorithm. The adSQI1, adSQI2, tHR, and rHR characteristics were significantly different among the good, acceptable, and unacceptable ECGs. The ptSQI value was considerably higher in the good ECGs than in the acceptable and unacceptable ECGs. The ECG segments of different quality levels were classified with an accuracy of 96.74% by using the proposed SQA method. The R waves and T waves were identified with accuracies of 99.95% and 99.57%, respectively, for segments that were classified as acceptable and/or good. The SQA-based ECG waveform delineation method can perform reliable analysis and has the potential to be applied in wearable ECG systems for the early diagnosis and prevention of cardiovascular diseases.
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McGill HC Jr, McMahan CA, Gidding SS (2008) Preventing heart disease in the 21st century: implications of the Pathobiological Determinants of Atherosclerosis in Youth (PDAY) study. Circulation 117(9):1216–1227
Jain SK, Bhaumik B (2017) An energy efficient ECG signal processor detecting cardiovascular diseases on smartphone. IEEE Trans Biomed Circuits Syst 11(2):314–323
Köhler BU, Hennig C, Orglmeister R (2002) The principles of software QRS detection. IEEE Eng Med Biol Mag 21(1):42–57
Alaei S, Wang S, Anaya P, Patwardhan A (2020) Co-occurrence and phase relationship between alternans of the R wave amplitude (RWAA) and of the T wave (TWA) in ECGs. Comput Biol Med 121:103785
El-Battrawy I, Lan H, Cyganek L, Zhao Z, Li X, Buljubasic F, Lang S, Yücel G, Sattler K, Zimmermann WH, Utikal J, Wieland T, Ravens U, Borggrefe M, Zhou XB, Akin I (2018) Modeling short QT syndrome using human-induced pluripotent stem cell-derived cardiomyocytes. J Am Heart Assoc 7(7):e007394
Rajendra Acharya U, Paul Joseph K, Kannathal N, Lim CM, Suri JS (2006) Heart rate variability: a review. Med Biol EngComput 44(12):1031–1051
Feeny AK, Chung MK, Madabhushi A, Attia ZI, Cikes M, Firouznia M et al (2020) Artificial intelligence and machine learning in arrhythmias and cardiac electrophysiology. Circ Arrhythm Electrophysiol 13(8):e007952
Drew BJ, Califf RM, Funk M, Kaufman ES, Krucoff MW, Laks MM, et al (2004) American Heart Association; Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young. Practice standards for electrocardiographic monitoring in hospital settings: an American Heart Association scientific statement from the Councils on Cardiovascular Nursing, Clinical Cardiology, and Cardiovascular Disease in the Young: endorsed by the International Society of Computerized Electrocardiology and the American Association of Critical-Care Nurses. Circulation 110(17):2721–2746.
Attia ZI, Noseworthy PA, Lopez-Jimenez F, Asirvatham SJ, Deshmukh AJ, Gersh BJ et al (2019) An artificial intelligence-enabled ECG algorithm for the identification of patients with atrial fibrillation during sinus rhythm: a retrospective analysis of outcome prediction. Lancet 394(10201):861–867
Laferriere P, Chan ADC, Lemaire ED (2011) Surface electromyographic signals using dry electrodes. IEEE Trans Instrum Meas 60(10):3259–3268
Miao F, Cheng Y, He Y, He Q, Li Y (2015) A wearable context-aware ECG monitoring system integrated with built-in kinematic sensors of the smartphone. Sensors (Basel) 15(5):11465–114684
Huang S, Li J, Zhang P, Zhang W (2018) Detection of mental fatigue state with wearable ECG devices. Int J Med Inform 119:39–46
Koshy AN, Sajeev JK, Nerlekar N, Brown AJ, Rajakariar K, Zureik M et al (2018) Smart watches for heart rate assessment in atrial arrhythmias. Int J Cardiol 266:124–127
Li M, Xiong W, Li Y (2020) Wearable measurement of ECG signals based on smart clothing. Int J Telemed Appl 2020:6329360
Tian Y, Abdizadeh M, Mahnam A, Bhattachan P, Meghrazi MA et al (2020) Modeling and reconstructing textile sensor noise: implications for wearable technology. Annu Int Conf IEEE Eng Med Biol Soc 2020:4563–4566
Satija U, Ramkumar B, Manikandan MS (2018) Automated ECG noise detection and classification system for unsupervised healthcare monitoring. IEEE J Biomed Health Inform 22(3):722–732
Moeyersons J, Smets E, Morales J, Villa A, De Raedt W, Testelmans D et al (2019) Artefact detection and quality assessment of ambulatory ECG signals. Comput Methods Programs Biomed 182:105050
Smital L, Haider CR, Vitek M, Leinveber P, Jurak P, Nemcova A et al (2020) Real-time quality assessment of long-term ECG signals recorded by wearables in free-living conditions. IEEE Trans Biomed Eng 67(10):2721–2734
Di Marco LY, Chiari L (2011) A wavelet-based ECG delineation algorithm for 32-bit integer online processing. Biomed Eng Online 10:23
Berset T, Geng D, Romero I (2012) An optimized DSP implementation of adaptive filtering and ICA for motion artifact reduction in ambulatory ECG monitoring. Annu Int Conf IEEE Eng Med Biol Soc 2012:6496–6499
Wang Z, Wan F, Wong CM, Zhang L (2016) Adaptive Fourier decomposition based ECG denoising. Comput Biol Med 77:195–205
Paul JS, Reddy MR, Kumar VJ (2000) A transform domain SVD filter for suppression of muscle noise artefacts in exercise ECG’s. IEEE Trans Biomed Eng 47(5):654–663
Chen M, Zhang X, Chen X, Zhu M, Li G, Zhou P (2016) FastICA peel-off for ECG interference removal from surface EMG. Biomed Eng Online 15(1):65
Jekova I, Krasteva V, Christov I, Abächerli R (2012) Threshold-based system for noise detection in multilead ECG recordings. Physiol Meas 33(9):1463–1477
Castiglioni P, Meriggi P, Faini A, Rienzo MD (2011) Cepstral based approach for online quantification of ECG quality in freely moving subjects. Computing in Cardiology 38:625–628
Xia H, Garcia GA, Bains J, Wortham DC, Zhao X (2012) Matrix of regularity for improving the quality of ECGs. Physiol Meas 33(9):1535–1548
Satija U, Ramkumar B, Manikandan MS (2017) Real-time signal quality-aware ECG telemetry system for IoT-based health care monitoring. IEEE Internet Things J 4(3):815–823
Satija U, Ramkumar B, Manikandan MS (2018) A review of signal processing techniques for electrocardiogram signal quality assessment. IEEE Rev Biomed Eng 11:36–52
Ong ME, Lee Ng CH, Goh K, Liu N, Koh ZX, Shahidah N et al (2012) Prediction of cardiac arrest in critically ill patients presenting to the emergency department using a machine learning score incorporating heart rate variability compared with the modified early warning score. Crit Care 16(3):R108
Verrier RL, Ikeda T (2013) Ambulatory ECG-based T-wave alternans monitoring for risk assessment and guiding medical therapy: mechanisms and clinical applications. Prog Cardiovasc Dis 56(2):172–185
Holkeri A, Eranti A, Haukilahti MAE, Kerola T, Kenttä TV, Tikkanen JT et al (2020) Predicting sudden cardiac death in a general population using an electrocardiographic risk score. Heart 106(6):427–433
Abdul-Kadir NA, Mat Safri N, Othman MA (2016) Dynamic ECG features for atrial fibrillation recognition. Comput Methods Programs Biomed 136:143–150
Li Q, Rajagopalan C, Clifford GD (2014) A machine learning approach to multi-level ECG signal quality classification. Comput Methods Programs Biomed 117(3):435–447
Clifford GD, Behar J, Li Q, Rezek I (2012) Signal quality indices and data fusion for determining clinical acceptability of electrocardiograms. Physiol Meas 33(9):1419–1433
Huerta A, Martínez-Rodrigo A, González V, Quesada A, Rieta J, et al (2019) Quality assessment of very long-term ECG recordings using a convolutional neural network. 2019 E-Health and Bioengineering Conference (EHB). IEEE, pp 1–4.
Behar J, Johnson A, Clifford GD, Oster J (2014) A comparison of single channel fetal ECG extraction methods. Ann Biomed Eng 42(6):1340–1353
Behar J, Oster J, Clifford GD (2014) Combining and benchmarking methods of foetal ECG extraction without maternal or scalp electrode data. Physiol Meas 35(8):1569–1589
Johnson AE, Behar J, Andreotti F, Clifford GD, Oster J (2015) Multimodal heart beat detection using signal quality indices. Physiol Meas 36(8):1665–1677
Ranjith P, Baby P, Joseph P (2003) ECG analysis using wavelet transform: application to myocardial ischemia detection. ITBM-RBM 24(1):44–47
Moody GB, Mark RG (1982) Development and evaluation of a 2-lead ecg analysis program. Comput Cardiol 9:39–44
Li Q, Mark RG, Clifford GD (2008) Robust heart rate estimation from multiple asynchronous noisy sources using signal quality indices and a Kalman filter. Physiol Meas 29(1):15–32
Behar J, Oster J, Li Q, Clifford GD (2013) ECG signal quality during arrhythmia and its application to false alarm reduction. IEEE Trans Biomed Eng 60(6):1660–1666
Liu C, Zhang X, Zhao L, Liu F, Chen X, Yao Y, Li J (2018) Signal quality assessment and lightweight QRS detection for wearable ECG SmartVest system. IEEE Internet Things J 6:1363–1374
Castro ID, Varon C, Torfs T, Van Huffel S, Puers R, Van Hoof C (2018) Evaluation of a multichannel non-contact ECG system and signal quality algorithms for sleep apnea detection and monitoring. Sensors (Basel) 18(2):577
Nardelli M, Ianata A, Valenza G, Felicib M, Baraglib P, Scilingoa EP (2020) A tool for the real-time evaluation of ECG signal quality and activity: application to submaximal treadmill test in horses. Biomedical Signal Processing and Control 56:101666
Hayn D, Jammerbund B, Schreier G (2011) ECG quality assessment for patient empowerment in mHealth applications. Computing in Cardiology 38:353–356
Orphanidou C, Bonnici T, Charlton P, Clifton D, Vallance D, Tarassenko L (2015) Signal-quality indices for the electrocardiogram and photoplethysmogram: derivation and applications to wireless monitoring. IEEE J Biomed Health Inform 19(3):832–838
Redmond SJ, Xie Y, Chang D, Basilakis J, Lovell NH (2012) Electrocardiogram signal quality measures for unsupervised telehealth environments. Physiol Meas 33(9):1517–1533
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This work was supported by the National Natural Science Foundation of China (NSFC31771070) and the Natural Science Foundation Project of Chongqing (cstc2017jcyjBX0053).
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Xie, J., Peng, L., Wei, L. et al. A signal quality assessment–based ECG waveform delineation method used for wearable monitoring systems. Med Biol Eng Comput 59, 2073–2084 (2021). https://doi.org/10.1007/s11517-021-02425-8
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DOI: https://doi.org/10.1007/s11517-021-02425-8