In this paper, we investigate the performance of Thorup's algorithm by comparing it to Dijkstra's algorithm for large-scale network simulations. One of the challenges toward the realization of large-scale network simulations is the efficient execution to find shortest paths in a graph with N vertices and M edges. The time complexity for solving a single-source shortest path (SSSP) problem with Dijkstra's algorithm with a binary heap (DIJKSTRA-BH) is O((M+N)log N). An sophisticated algorithm called Thorup's algorithm has been proposed. The original version of Thorup's algorithm (THORUP-FR) has the time complexity of O(M+N). A simplified version of Thorup's algorithm (THORUP-KL) has the time complexity of O(Mα(N)+N) where α(N) is the functional inverse of the Ackerman function. In this paper, we compare the performances (i.e., execution time and memory consumption) of THORUP-KL and DIJKSTRA-BH since it is known that THORUP-FR is at least ten times slower than Dijkstra's algorithm with a Fibonaccii heap. We find that (1) THORUP-KL is almost always faster than DIJKSTRA-BH for large-scale network simulations, and (2) the performances of THORUP-KL and DIJKSTRA-BH deviate from their time complexities due to the presence of the memory cache in the microprocessor.