C1QA
C1QA (Complement C1q A chain) هوَ بروتين يُشَفر بواسطة جين C1QA في الإنسان.[1][2]
الوظيفة
[عدل]![[أيقونة]](http://upload.wikimedia.org/wikipedia/commons/thumb/d/dd/Crystal_xedit.svg/40px-Crystal_xedit.svg.png){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
[عدل] | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
[عدل]- ^ "Entrez Gene: C1QA complement component 1, q subcomponent, A chain". مؤرشف من الأصل في 2010-12-05.
- ^ Sellar GC، Cockburn D، Reid KB (مارس 1992). "Localization of the gene cluster encoding the A, B, and C chains of human C1q to 1p34.1-1p36.3". Immunogenetics. ج. 35 ع. 3: 214–6. DOI:10.1007/bf00185116. PMID:1537612.
قراءة متعمقة
[عدل]- Petry F (1999). "Molecular basis of hereditary C1q deficiency". Immunobiology. ج. 199 ع. 2: 286–94. DOI:10.1016/s0171-2985(98)80033-8. PMID:9777412.
- Thielens NM، Tacnet-Delorme P، Arlaud GJ (2003). "Interaction of C1q and mannan-binding lectin with viruses". Immunobiology. ج. 205 ع. 4–5: 563–74. DOI:10.1078/0171-2985-00155. PMID:12396016.
- Reid KB (1976). "Isolation, by partial pepsin digestion, of the three collagen-like regions present in subcomponent Clq of the first component of human complement". Biochem. J. ج. 155 ع. 1: 5–17. PMC:1172796. PMID:7240.
- Reid KB (1979). "Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement". Biochem. J. ج. 179 ع. 2: 367–71. PMC:1186634. PMID:486087.
- Krumdieck R، Höök M، Rosenberg LC، Volanakis JE (1992). "The proteoglycan decorin binds C1q and inhibits the activity of the C1 complex". J. Immunol. ج. 149 ع. 11: 3695–701. PMID:1431141.
- Sellar GC، Blake DJ، Reid KB (1991). "Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q". Biochem. J. ج. 274 ع. 2: 481–90. PMC:1150164. PMID:1706597.
- Ebenbichler CF، Thielens NM، Vornhagen R، وآخرون (1992). "Human immunodeficiency virus type 1 activates the classical pathway of complement by direct C1 binding through specific sites in the transmembrane glycoprotein gp41". J. Exp. Med. ج. 174 ع. 6: 1417–24. DOI:10.1084/jem.174.6.1417. PMC:2119058. PMID:1744579.
- Su H، Boackle RJ (1991). "Interaction of the envelope glycoprotein of human immunodeficiency virus with C1q and fibronectin under conditions present in human saliva". Mol. Immunol. ج. 28 ع. 8: 811–7. DOI:10.1016/0161-5890(91)90044-K. PMID:1875953.
- Busby TF، Ingham KC (1990). "NH2-terminal calcium-binding domain of human complement C1s- mediates the interaction of C1r- with C1q". Biochemistry. ج. 29 ع. 19: 4613–8. DOI:10.1021/bi00471a016. PMID:2372546.
- Bing DH، Almeda S، Isliker H، وآخرون (1982). "Fibronectin binds to the C1q component of complement". Proc. Natl. Acad. Sci. U.S.A. ج. 79 ع. 13: 4198–201. DOI:10.1073/pnas.79.13.4198. PMC:346605. PMID:6981115.
- Reid KB، Gagnon J، Frampton J (1982). "Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement". Biochem. J. ج. 203 ع. 3: 559–69. PMC:1158269. PMID:6981411.
- Stoiber H، Thielens NM، Ebenbichler C، وآخرون (1994). "The envelope glycoprotein of HIV-1 gp120 and human complement protein C1q bind to the same peptides derived from three different regions of gp41, the transmembrane glycoprotein of HIV-1, and share antigenic homology". Eur. J. Immunol. ج. 24 ع. 2: 294–300. DOI:10.1002/eji.1830240203. PMID:7507842.
- Prohászka Z، Hidvégi T، Ujhelyi E، وآخرون (1995). "Interaction of complement and specific antibodies with the external glycoprotein 120 of HIV-1". Immunology. ج. 85 ع. 2: 184–9. PMC:1383879. PMID:7642209.
- Stoiber H، Ebenbichler CF، Thielens NM، وآخرون (1995). "HIV-1 rsgp41 depends on calcium for binding of human c1q but not for binding of gp120". Mol. Immunol. ج. 32 ع. 5: 371–4. DOI:10.1016/0161-5890(94)00156-U. PMID:7739575.
- Gulati P، Guc D، Lemercier C، وآخرون (1994). "Expression of the components and regulatory proteins of the classical pathway of complement in normal and diseased synovium". Rheumatol. Int. ج. 14 ع. 1: 13–9. DOI:10.1007/BF00302666. PMID:7939135.
- Gulati P، Lemercier C، Guc D، وآخرون (1994). "Regulation of the synthesis of C1 subcomponents and C1-inhibitor". Behring Inst. Mitt. ع. 93: 196–203. PMID:8172568.
- Ghebrehiwet B، Lim BL، Peerschke EI، وآخرون (1994). "Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q". J. Exp. Med. ج. 179 ع. 6: 1809–21. DOI:10.1084/jem.179.6.1809. PMC:2191527. PMID:8195709.
- Thielens NM، Bally IM، Ebenbichler CF، وآخرون (1994). "Further characterization of the interaction between the C1q subcomponent of human C1 and the transmembrane envelope glycoprotein gp41 of HIV-1". J. Immunol. ج. 151 ع. 11: 6583–92. PMID:8245486.
- Hidvégi T، Prohászka Z، Ujhelyi E، وآخرون (1994). "Studies on the mechanism of complement-mediated inhibition of antibody binding to HIV gp41". Clin. Exp. Immunol. ج. 94 ع. 3: 490–3. DOI:10.1111/j.1365-2249.1993.tb08223.x. PMC:1534428. PMID:8252810.
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