Many techniques have been developed for detection of chatter in milling operations. However, thei... more Many techniques have been developed for detection of chatter in milling operations. However, their practical applications have not been common since expensive dynamometers and serious computation power is needed. Index Based Reasoning (IBR) was proposed in this study for chatter detection. IBR allow the engineers to program microcontrollers easily for diagnostic applications. In this paper, IBR was used for detection
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2015
Spontaneous "non-moyamoya" arterial occlusion of the intracranial arteries is very unus... more Spontaneous "non-moyamoya" arterial occlusion of the intracranial arteries is very unusual. Progressive occlusion of a major intracranial artery, independently from the etiology, can lead to the development of collateral arterial networks that supply blood flow to distal territories beyond the occlusion. These collateral arteries are typically small and conduct low flows, but the hemodynamic stress within them can lead to aneurysm formation within the collateral network. In this report we present a case of spontaneous internal carotid artery occlusion and collateral network aneurysm for the first time in the literature and discuss the main features of the etiology and endovascular treatment of this rare, challenging aneurysm.
Damaged or broken parts are generally too expensive to replace, or are no longer available. RE ca... more Damaged or broken parts are generally too expensive to replace, or are no longer available. RE can be defined as: ‘Systematic evaluation of a product with the purpose of replication. This involves design of a new part, copy of an existing part, recovery of a damaged or broken part, improvement of model precision and inspection of a numerical model. Advantages
The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of tit... more The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of titanium dioxide nanoparticles (nano-TiO2) and its microparticulated form has been evaluated in human embryonic kidney (HEK293) and in mouse embryonic fibroblast (NIH/3T3) cells. Nano-TiO2 of two different sizes (21 and 50 nm) were used in this study. The comet assay, with and without the use of FPG enzyme, the micronucleus assay and the soft-agar colony assay were used. For both the comet assay and the frequency of micronuclei a statistically significant induction of DNA damage, was observed at the highest dose tested (1000 µg/mL). No oxidative DNA damage induction was observed when the comet assay was complemented with the use of FPG enzyme. Furthermore, long-term exposure to nano-TiO2 has also proved to induce cell-transformation promoting cell-anchorage independent growth in soft-agar. Results were similar for the two nano-TiO2 sizes. Negative results were obtained when the microparticu...
The arterial pattern of the upper limb is one of the systems that shows a large number of variati... more The arterial pattern of the upper limb is one of the systems that shows a large number of variations in the adult human body. Most of these variations occur in either the radial or ulnar artery; brachial artery variations are less common. In this case report we describe the anomaly in the formation of the brachial artery system. Appreciation of variations in the upper extremity vasculature is essential to prevent injury, particularly in patients undergoing arteriography.
The Journal of Thoracic and Cardiovascular Surgery, 2008
Prophylactic treatment with carbamazepine has been shown to reduce the cerebral damage and neurol... more Prophylactic treatment with carbamazepine has been shown to reduce the cerebral damage and neurologic deficit in ischemic conditions. A randomized controlled study based on a rabbit model was designed to study the effect of carbamazepine on a spinal cord ischemic reperfusion injury. Thirty New Zealand rabbits were randomly assigned to 1 of the 2 groups (n = 15 per group): group I (control group) and group II (carbamazepine group). Spinal cord ischemia was induced by infrarenal aortic crossclamp for 25 minutes in both groups. Functional evaluation with the Tarlov score during a 2-day observation period and histopathologic assessment of the lumbar spinal cord were performed. Changes in spinal cord morphology were observed with hematoxylin-eosin staining and electron microscopy. Gray matter damage was assessed on the basis of the number of normal neurons in the ventral horn. Diffuse destruction of gray matter with moderate to severe vacuolization and essentially no normal ganglion cells was observed in the spinal cord of rabbits in the control group, whereas specimens of rabbits assigned to the carbamazepine group showed ganglion cells with normal nuclei and cytoplasm (P < .0001). Neurologic impairment was significantly attenuated in the carbamazepine group compared with the Tarlov scores of the control group (P < .0001 at day 2). Carbamazepine may protect the spinal cord from ischemic reperfusion injury that is associated with ameliorated neurologic and histopathologic results.
Many techniques have been developed for detection of chatter in milling operations. However, thei... more Many techniques have been developed for detection of chatter in milling operations. However, their practical applications have not been common since expensive dynamometers and serious computation power is needed. Index Based Reasoning (IBR) was proposed in this study for chatter detection. IBR allow the engineers to program microcontrollers easily for diagnostic applications. In this paper, IBR was used for detection
Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2015
Spontaneous "non-moyamoya" arterial occlusion of the intracranial arteries is very unus... more Spontaneous "non-moyamoya" arterial occlusion of the intracranial arteries is very unusual. Progressive occlusion of a major intracranial artery, independently from the etiology, can lead to the development of collateral arterial networks that supply blood flow to distal territories beyond the occlusion. These collateral arteries are typically small and conduct low flows, but the hemodynamic stress within them can lead to aneurysm formation within the collateral network. In this report we present a case of spontaneous internal carotid artery occlusion and collateral network aneurysm for the first time in the literature and discuss the main features of the etiology and endovascular treatment of this rare, challenging aneurysm.
Damaged or broken parts are generally too expensive to replace, or are no longer available. RE ca... more Damaged or broken parts are generally too expensive to replace, or are no longer available. RE can be defined as: ‘Systematic evaluation of a product with the purpose of replication. This involves design of a new part, copy of an existing part, recovery of a damaged or broken part, improvement of model precision and inspection of a numerical model. Advantages
The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of tit... more The in vitro genotoxic and the soft-agar anchorage independent cell transformation ability of titanium dioxide nanoparticles (nano-TiO2) and its microparticulated form has been evaluated in human embryonic kidney (HEK293) and in mouse embryonic fibroblast (NIH/3T3) cells. Nano-TiO2 of two different sizes (21 and 50 nm) were used in this study. The comet assay, with and without the use of FPG enzyme, the micronucleus assay and the soft-agar colony assay were used. For both the comet assay and the frequency of micronuclei a statistically significant induction of DNA damage, was observed at the highest dose tested (1000 µg/mL). No oxidative DNA damage induction was observed when the comet assay was complemented with the use of FPG enzyme. Furthermore, long-term exposure to nano-TiO2 has also proved to induce cell-transformation promoting cell-anchorage independent growth in soft-agar. Results were similar for the two nano-TiO2 sizes. Negative results were obtained when the microparticu...
The arterial pattern of the upper limb is one of the systems that shows a large number of variati... more The arterial pattern of the upper limb is one of the systems that shows a large number of variations in the adult human body. Most of these variations occur in either the radial or ulnar artery; brachial artery variations are less common. In this case report we describe the anomaly in the formation of the brachial artery system. Appreciation of variations in the upper extremity vasculature is essential to prevent injury, particularly in patients undergoing arteriography.
The Journal of Thoracic and Cardiovascular Surgery, 2008
Prophylactic treatment with carbamazepine has been shown to reduce the cerebral damage and neurol... more Prophylactic treatment with carbamazepine has been shown to reduce the cerebral damage and neurologic deficit in ischemic conditions. A randomized controlled study based on a rabbit model was designed to study the effect of carbamazepine on a spinal cord ischemic reperfusion injury. Thirty New Zealand rabbits were randomly assigned to 1 of the 2 groups (n = 15 per group): group I (control group) and group II (carbamazepine group). Spinal cord ischemia was induced by infrarenal aortic crossclamp for 25 minutes in both groups. Functional evaluation with the Tarlov score during a 2-day observation period and histopathologic assessment of the lumbar spinal cord were performed. Changes in spinal cord morphology were observed with hematoxylin-eosin staining and electron microscopy. Gray matter damage was assessed on the basis of the number of normal neurons in the ventral horn. Diffuse destruction of gray matter with moderate to severe vacuolization and essentially no normal ganglion cells was observed in the spinal cord of rabbits in the control group, whereas specimens of rabbits assigned to the carbamazepine group showed ganglion cells with normal nuclei and cytoplasm (P < .0001). Neurologic impairment was significantly attenuated in the carbamazepine group compared with the Tarlov scores of the control group (P < .0001 at day 2). Carbamazepine may protect the spinal cord from ischemic reperfusion injury that is associated with ameliorated neurologic and histopathologic results.
Uploads
Papers by Bülent Kaya