布西丁
外观
臨床資料 | |
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ATC碼 | |
识别信息 | |
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CAS号 | 1083-57-4 |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.012.827 |
化学信息 | |
化学式 | C12H17NO3 |
摩尔质量 | 223.27 g·mol−1 |
3D模型(JSmol) | |
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布西丁(英語:Bucetin)是一种曾经用于镇痛退热的药物。[1][2]从化学结构上来看,布西丁和非那西丁相似,并且都有引发癌变的风险。[3]由于其肾毒性,布西丁于1986年被撤回。[4]
参见
[编辑]参考资料
[编辑]- ^ J. Elks. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014: 184– [2021-04-12]. ISBN 978-1-4757-2085-3. (原始内容存档于2021-04-12).
- ^ WHOCC - ATC/DDD Index. WHO Collaborating Centre for Drug Statistics Methodology. December 19, 2013 [2021-04-12]. (原始内容存档于2021-01-28).
- ^ Togei K, Sano N, Maeda T, Shibata M, Otsuka H. Carcinogenicity of bucetin in (C57BL/6 X C3H)F1 mice. Journal of the National Cancer Institute. November 1987, 79 (5): 1151–8. PMID 3479641. doi:10.1093/jnci/79.5.1151.
- ^ Fung M, Thornton A, Mybeck K, Wu JH, Hornbuckle K, Muniz E. Evaluation of the Characteristics of Safety Withdrawal of Prescription Drugs from Worldwide Pharmaceutical Markets-1960 to 1999. Drug Information Journal. 2001, 35: 293–317. doi:10.1177/009286150103500134.