Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice (Q33853415)

29 July 2017

title

Transient gene transfer and expression of Smad7 prevents bleomycin-induced lung fibrosis in mice (English)

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29 July 2017

1 reference

A Nakao

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29 July 2017

M Fujii

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29 July 2017

R Matsumura

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29 July 2017

K Kumano

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29 July 2017

Y Saito

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29 July 2017

K Miyazono

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29 July 2017

I Iwamoto

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29 July 2017

language of work or name

English

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publication date

1 July 1999

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Journal of Clinical Investigation

29 July 2017

published in

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29 July 2017

volume

104

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29 July 2017

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29 July 2017

page(s)

5-11

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Status of gene therapy for cystic fibrosis lung disease

29 July 2017

cites work

1 reference

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Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

5 July 2018

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TGF-beta signal transduction

5 July 2018

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Transfer of tumor necrosis factor-alpha to rat lung induces severe pulmonary inflammation and patchy interstitial fibrogenesis with induction of transforming growth factor-beta1 and myofibroblasts

5 July 2018

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Smad-dependent transcriptional activation of human type VII collagen gene (COL7A1) promoter by transforming growth factor-beta

5 July 2018

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

5 July 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

5 July 2018

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

5 July 2018

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5 July 2018

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Vascular MAD s: Two novel MAD -related genes selectively inducible by flow in human vascular endothelium

5 July 2018

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5 July 2018

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Prevention of bleomycin-induced pulmonary fibrosis after adenovirus-mediated transfer of the bacterial bleomycin resistance gene

5 July 2018

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

5 July 2018

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5 July 2018

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5 July 2018

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Regulation of alveolar macrophage transforming growth factor-beta secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat

5 July 2018

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Altered expression of small proteoglycans, collagen, and transforming growth factor-beta 1 in developing bleomycin-induced pulmonary fibrosis in rats.

5 July 2018

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5 July 2018

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5 July 2018

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Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis

5 July 2018

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5 July 2018

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Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis

5 July 2018

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Efficient selection for high-expression transfectants with a novel eukaryotic vector

5 July 2018

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Spontaneous increase of transforming growth factor beta production by bronchoalveolar mononuclear cells of patients with systemic autoimmune diseases affecting the lung

5 July 2018

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Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer

5 July 2018

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Smad6 inhibits signalling by the TGF-β superfamily

29 October 2018

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The L45 loop in type I receptors for TGF-beta family members is a critical determinant in specifying Smad isoform activation

29 October 2018

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12 December 2020

Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

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12 December 2020

The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid

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12 December 2020

Determination of hydroxyproline by high pressure liquid chromatography

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12 December 2020

Interleukin-12 prevents antigen-induced eosinophil recruitment into mouse airways

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12 December 2020

Gene expression of types I and III collagen, decorin, matrix metalloproteinases and tissue inhibitors of metalloproteinases in skin fibroblasts from patients with systemic sclerosis

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12 December 2020

Simultaneous or delayed administration of hepatocyte growth factor equally represses the fibrotic changes in murine lung injury induced by bleomycin. A morphologic study

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12 December 2020

Identifiers

DOI

10.1172/JCI6094

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29 July 2017

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29 July 2017

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