Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin (Q33826525)

29 July 2017

title

Runx1 directly promotes proliferation of hair follicle stem cells and epithelial tumor formation in mouse skin (English)

1 reference

29 July 2017

main subject

hair follicle stem cell

1 reference

Tudorita Tumbar

0 references

Ralf Paus

0 references

Charlene S L Hoi

1 reference

29 July 2017

Song Eun Lee

1 reference

29 July 2017

Shu-Yang Lu

1 reference

29 July 2017

David J McDermitt

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29 July 2017

Karen M Osorio

1 reference

29 July 2017

Caroline M Piskun

1 reference

29 July 2017

Rachel M Peters

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29 July 2017

language of work or name

English

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publication date

22 March 2010

1 reference

Molecular and Cellular Biology

29 July 2017

published in

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

2518-2536

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Examination of the expanding pathways for the regulation of p21 expression and activity

29 July 2017

cites work

1 reference

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4 July 2018

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Distinct self-renewal and differentiation phases in the niche of infrequently dividing hair follicle stem cells.

4 July 2018

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RUNX genes find a niche in stem cell biology

4 July 2018

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4 July 2018

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4 July 2018

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RUNX1 and its fusion oncoprotein derivative, RUNX1-ETO, induce senescence-like growth arrest independently of replicative stress

4 July 2018

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Lrig1 expression defines a distinct multipotent stem cell population in mammalian epidermis

4 July 2018

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An orthotopic endometrial cancer mouse model demonstrates a role for RUNX1 in distant metastasis.

4 July 2018

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4 July 2018

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The hair follicle as a dynamic miniorgan

4 July 2018

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A two-step mechanism for stem cell activation during hair regeneration

4 July 2018

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Constitutive activation and targeted disruption of signal transducer and activator of transcription 3 (Stat3) in mouse epidermis reveal its critical role in UVB-induced skin carcinogenesis.

4 July 2018

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Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

4 July 2018

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Runx transcription factors in neuronal development

4 July 2018

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Cutaneous cancer stem cell maintenance is dependent on beta-catenin signalling

4 July 2018

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Impaired skin and hair follicle development in Runx2 deficient mice

4 July 2018

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Runx1 modulates developmental, but not injury-driven, hair follicle stem cell activation.

4 July 2018

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Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration

4 July 2018

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A perspective on murine keratinocyte stem cells as targets of chemically induced skin cancer

4 July 2018

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Scratching the surface of skin development

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Epithelial skin stem cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Dynamic expression of Runx1 in skin affects hair structure

4 July 2018

1 reference

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Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

4 July 2018

1 reference

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Epithelial stem cells: a folliculocentric view

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Normal and transforming functions of RUNX1: a perspective

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

AML1 deletion in adult mice causes splenomegaly and lymphomas.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Long-term renewal of hair follicles from clonogenic multipotent stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

The RUNX genes: gain or loss of function in cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Hair follicle stem cells in the lower bulge form the secondary germ, a biochemically distinct but functionally equivalent progenitor cell population, at the termination of catagen.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Cell cycle inhibitors in normal and tumor stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

RUNX1 transformation of primary embryonic fibroblasts is revealed in the absence of p53.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Runx transcription factors and the developmental balance between cell proliferation and differentiation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Core-binding factors in haematopoiesis and leukaemia

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

AML1 stimulates G1 to S progression via its transactivation domain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

A comprehensive guide for the accurate classification of murine hair follicles in distinct hair cycle stages

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Two distinct signaling pathways in hair cycle induction: Stat3-dependent and -independent pathways

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

p21(WAF1/Cip1) functions as a suppressor of malignant skin tumor formation and a determinant of keratinocyte stem-cell potential

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Generalized lacZ expression with the ROSA26 Cre reporter strain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Hair follicles, stem cells, and skin cancer

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Growth inhibition and induction of differentiation of t(8;21) acute myeloid leukemia cells by the DNA-binding domain of PEBP2 and the AML1/MTG8(ETO)-specific antisense oligonucleotide

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Radiation-induced cell cycle arrest compromised by p21 deficiency

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Tissue-specific and differentiation-specific expression of a human K14 keratin gene in transgenic mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Three clonal types of keratinocyte with different capacities for multiplication

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Association of phosphorylated epidermal growth factor receptor with survival in patients with locally advanced non-small cell lung cancer treated with radiotherapy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of DeltaNp63.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Regulation of RUNX1/AML1 during the G2/M transition.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Runx1 transcription factor is involved in the regulation of KAP5 gene expression in human hair follicles

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

The expression of p63 in actinic keratoses, seborrheic keratosis, and cutaneous squamous cell carcinomas

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Mouse skin is particularly susceptible to tumor initiation during early anagen of the hair cycle: possible involvement of hair follicle stem cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2863705

Diminution of the AML1 transcription factor function causes differential effects on the fates of CD4 and CD8 single-positive T cells

29 October 2018

1 reference

12 December 2020

Morphogenesis and renewal of hair follicles from adult multipotent stem cells

1 reference

12 December 2020

FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin

1 reference

12 December 2020

Cylindroma as tumor of hair follicle origin

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.01308-09

1 reference

29 July 2017

1 reference

29 July 2017

1 reference