Inactivation of the apoptosis effector Apaf-1 in malignant melanoma (Q31984891)

5 July 2017

title

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma (English)

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5 July 2017

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Soengas MS

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5 July 2017

Capodieci P

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Polsky D

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Mora J

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Opitz-Araya X

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5 July 2017

Herman JG

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Gerald WL

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Lazebnik YA

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Cordón-Cardó C

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Lowe SW

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5 July 2017

language of work or name

English

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publication date

1 January 2001

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5 July 2017

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volume

409

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5 July 2017

issue

6817

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5 July 2017

page(s)

207-211

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Malignant melanoma: modern black plague and genetic black box.

5 July 2017

cites work

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7 January 2021

The chemoresistance of human malignant melanoma: an update.

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7 January 2021

Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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7 January 2021

Oncogene-dependent apoptosis is mediated by caspase-9.

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7 January 2021

DNA hypermethylation in tumorigenesis: epigenetics joins genetics

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7 January 2021

DNA methylation: past, present and future directions

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7 January 2021

Methylation-induced repression--belts, braces, and chromatin

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7 January 2021

CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locus

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7 January 2021

Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 gene

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7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

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7 January 2021

Mitochondria and apoptosis

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Caspase-9 and APAF-1 form an active holoenzyme

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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7 January 2021

Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis

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7 January 2021

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

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7 January 2021

Frameshift mutations in Fas, Apaf-1 and Bcl-10 in gastro-intestinal cancer of the microsatellite mutator phenotype

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7 January 2021

INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

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7 January 2021

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

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7 January 2021

Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets

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7 January 2021

Expression and targeting of the apoptosis inhibitor, survivin, in human melanoma

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7 January 2021

Inhibition of death receptor signals by cellular FLIP

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7 January 2021

Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.

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7 January 2021

Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changes

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7 January 2021

Automated in situ hybridization: diagnostic and research applications

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7 January 2021

Identifiers

DOI

10.1038/35051606

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Dimensions Publication ID

5 July 2017

1052418104

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