Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux (Q35023368)

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English	Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Combination of suboptimal doses of inhibitors targeting different domains of LtrMDR1 efficiently overcomes resistance of Leishmania spp. to Miltefosine by inhibiting drug efflux (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

1 reference

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inferred from title

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Leishmania

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based on heuristic

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José María Pérez-Victoria

object named as

José M Pérez-Victoria

1

0 references

Francisco Gamarro

object named as

Francisco Gamarro

12

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Maria Paola Costi

1 reference

ORCID Public Data File 2021

Attilio Di Pietro

10

object named as

Attilio Di Pietro

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Fernando Cortés-Selva

2

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Europe PubMed Central

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5 August 2017

Adriana Parodi-Talice

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

Boris I Bavchvarov

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

F Javier Pérez-Victoria

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Francisco Muñoz-Martínez

6

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Mathias Maitrejean

7

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

M Paola Costi

8

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Denis Barron

9

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Europe PubMed Central

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5 August 2017

Santiago Castanys

11

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5 August 2017

language of work or name

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publication date

1 September 2006

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5 August 2017

Antimicrobial Agents and Chemotherapy

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5 August 2017

50

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Europe PubMed Central

PubMed publication ID

5 August 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

3102-3110

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Mechanisms of drug action and drug resistance in Leishmania as basis for therapeutic target identification and design of antileishmanial modulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2.

1 reference

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A phase I and pharmacologic study of the MDR converter GF120918 in combination with doxorubicin in patients with advanced solid tumors

1 reference

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8 July 2018

Characterisation of Leishmania donovani promastigotes resistant to hexadecylphosphocholine (miltefosine).

1 reference

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8 July 2018

Leishmania donovani resistance to miltefosine involves a defective inward translocation of the drug

1 reference

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8 July 2018

RU49953: a non-hormonal steroid derivative that potently inhibits P-glycoprotein and reverts cellular multidrug resistance

1 reference

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8 July 2018

Oral miltefosine for Indian visceral leishmaniasis

1 reference

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8 July 2018

Multidrug resistance phenotype mediated by the P-glycoprotein-like transporter in Leishmania: a search for reversal agents

1 reference

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8 July 2018

ABC transporters in the protozoan parasite Leishmania.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

A policy for leishmaniasis with respect to the prevention and control of drug resistance

1 reference

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8 July 2018

Reversal of chloroquine resistance in Plasmodium falciparum using combinations of chemosensitizers

1 reference

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8 July 2018

Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator

1 reference

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8 July 2018

Reversal of multidrug resistance by the P-glycoprotein modulator, LY335979, from the bench to the clinic

1 reference

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8 July 2018

High-affinity binding of silybin derivatives to the nucleotide-binding domain of a Leishmania tropica P-glycoprotein-like transporter and chemosensitization of a multidrug-resistant parasite to daunomycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

Multiple recognition of various amphiphilic molecules by the multidrug resistance P-glycoprotein: molecular mechanisms and pharmacological consequences coming from functional interactions between various drugs

1 reference

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8 July 2018

P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.

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8 July 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

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8 July 2018

Correlation between the affinity of flavonoids binding to the cytosolic site of Leishmania tropica multidrug transporter and their efficiency to revert parasite resistance to daunomycin

1 reference

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8 July 2018

Plasmodium and Leishmania: the role of mdr genes in mediating drug resistance.

1 reference

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8 July 2018

Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid-binding sites on mouse P-glycoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

Altered drug membrane permeability in a multidrug-resistant Leishmania tropica line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

Binding of steroid modulators to recombinant cytosolic domain from mouse P-glycoprotein in close proximity to the ATP site.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

8 July 2018

Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1563564

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Crystal structure of the Src family tyrosine kinase Hck

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Reversal of P-glycoprotein-mediated multidrug resistance by a potent cyclopropyldibenzosuberane modulator, LY335979.

1 reference

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Apical membrane aminopeptidase appears at site of cell-cell contact in cultured kidney epithelial cells

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Breast tumor cell lines from pleural effusions

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12 December 2020

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12 December 2020

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Recombinant N-terminal nucleotide-binding domain from mouse P-glycoprotein. Overexpression, purification, and role of cysteine 430

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12 December 2020

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Competitive, non-competitive and cooperative interactions between substrates of P-glycoprotein as measured by its ATPase activity

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Identifiers

10.1128/AAC.00423-06

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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