Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease (Q21144949)

17 August 2022

Elizabeth Dorfman

Elizabeth

Dorfman

1 reference

17 August 2022

Samuel M Goldman

Samuel M

Goldman

1 reference

17 August 2022

Caroline M Tanner

Caroline M

Tanner

1 reference

17 August 2022

Joanna L

Mountain

Joanna L Mountain

1 reference

17 August 2022

Chuong B Do

Chuong B

1 reference

17 August 2022

Joyce Y Tung

Joyce Y

Tung

1 reference

17 August 2022

Amy K Kiefer

Amy K

Kiefer

1 reference

17 August 2022

Emily M Drabant

Emily M

Drabant

1 reference

17 August 2022

Uta Francke

Uta

Francke

1 reference

17 August 2022

J William Langston

J William

Langston

1 reference

17 August 2022

Nicholas Eriksson

Nicholas

Eriksson

1 reference

Creative Commons Attribution 4.0 International

17 August 2022

language of work or name

English

0 references

publication date

June 2011

0 references

0 references

0 references

0 references

e1002141

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start time

23 June 2011

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

describes a project that uses

genome-wide association study

1 reference

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies

inferred from title

cites work

1 reference

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Web-based, participant-driven studies yield novel genetic associations for common traits

19 March 2017

1 reference

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Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease

19 March 2017

1 reference

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Genome-wide association study reveals genetic risk underlying Parkinson's disease

19 March 2017

1 reference

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

19 March 2017

1 reference

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

19 March 2017

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LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase

19 March 2017

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A note on exact tests of Hardy-Weinberg equilibrium

19 March 2017

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Hereditary early-onset Parkinson's disease caused by mutations in PINK1

19 March 2017

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Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

19 March 2017

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

19 March 2017

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Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins

19 March 2017

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Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies

19 March 2017

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alpha-Synuclein locus triplication causes Parkinson's disease

19 March 2017

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

19 March 2017

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The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI

19 March 2017

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Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase

19 March 2017

1 reference

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Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology

19 March 2017

1 reference

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

19 March 2017

1 reference

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Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis

19 March 2017

1 reference

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Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

The human synaptotagmin IV gene defines an evolutionary break point between syntenic mouse and human chromosome regions but retains ligand inducibility and tissue specificity

19 March 2017

1 reference

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Parkinson disease in twins: an etiologic study

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

19 March 2017

1 reference

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Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.

19 March 2017

1 reference

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GCTA: a tool for genome-wide complex trait analysis

7 April 2017

1 reference

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Common SNPs explain a large proportion of the heritability for human height

7 April 2017

1 reference

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LocusZoom: regional visualization of genome-wide association scan results

7 April 2017

1 reference

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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

7 April 2017

1 reference

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Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

7 April 2017

1 reference

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Estimating missing heritability for disease from genome-wide association studies

7 April 2017

1 reference

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A machine learning pipeline for quantitative phenotype prediction from genotype data

12 September 2017

1 reference

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Familial aggregation of Parkinson's disease in a multiethnic community‐based case‐control study

12 September 2017

1 reference

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Risk prediction using genome‐wide association studies

12 September 2017

1 reference

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Frequency of known mutations in early-onset Parkinson disease: implication for genetic counseling: the consortium on risk for early onset Parkinson disease study

12 September 2017

1 reference

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The heritability of risk and age at onset of Parkinson's disease after accounting for known genetic risk factors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

The genetic interpretation of area under the ROC curve in genomic profiling

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Elastic-net regularization approaches for genome-wide association studies of rheumatoid arthritis

12 September 2017

1 reference

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Assessing the performance of prediction models: a framework for traditional and novel measures

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Multistage analysis strategies for genome-wide association studies: summary of group 3 contributions to Genetic Analysis Workshop 16.

12 September 2017

1 reference

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Sporadic cases are the norm for complex disease

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Mutations in GBA are associated with familial Parkinson disease susceptibility and age at onset

12 September 2017

1 reference

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Genomewide association study for susceptibility genes contributing to familial Parkinson disease

12 September 2017

1 reference

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Simultaneous analysis of all SNPs in genome-wide and re-sequencing association studies

12 September 2017

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Assessment of cumulative evidence on genetic associations: interim guidelines

12 September 2017

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ATP13A2 missense mutations in juvenile parkinsonism and young onset Parkinson disease

12 September 2017

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Genetic evidence for ubiquitin-specific proteases USP24 and USP40 as candidate genes for late-onset Parkinson disease

12 September 2017

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Genetics of Parkinson disease: paradigm shifts and future prospects.

12 September 2017

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Mutations in the glucocerebrosidase gene and Parkinson's disease in Ashkenazi Jews

12 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3121750

Deficits in memory and motor performance in synaptotagmin IV mutant mice

12 September 2017

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Role of NMDA receptor-dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries.

12 September 2017

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Use and misuse of the receiver operating characteristic curve in risk prediction

27 September 2017

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Genome-wide SNP assay reveals structural genomic variation, extended homozygosity and cell-line induced alterations in normal individuals

27 September 2017

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Gauging the performance of SNPs, biomarkers, and clinical factors for predicting risk of breast cancer

27 September 2017

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The role of inheritance in sporadic Parkinson's disease: evidence from a longitudinal study of dopaminergic function in twins

30 May 2018

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No evidence for heritability of Parkinson disease in Swedish twins.

21 January 2018

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Familial Aggregation of Parkinson's Disease in Iceland

21 January 2018

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Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002141

Mutations in RAI1 associated with Smith-Magenis syndrome

21 January 2018

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Trend tests for case-control studies of genetic markers: power, sample size and robustness

21 January 2018

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Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease

21 January 2018

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Complex segregation analysis of Parkinson's disease in the Finnish population

21 January 2018

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12 December 2020

Evaluating diagnostic tests: The area under the ROC curve and the balance of errors

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12 December 2020

Assessment of Improved Prediction Beyond Traditional Risk Factors

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12 December 2020

Increased risk of Parkinson's disease in parents and siblings of patients

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12 December 2020

Regularization and variable selection via the elastic net

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002141

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1371/JOURNAL.PGEN.1002141

1 reference

1 reference

1 reference

1 reference