Vacuolar protein sorting 25 homolog (Q21112846)

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mammalian protein found in Homo sapiens

• ELL-associated protein of 20 kDa
• dermal papilla-derived protein 9
• vacuolar protein-sorting-associated protein 25
• VPS25
• ESCRT-II complex subunit VPS25

edit

Language	Label	Description	Also known as
English	Vacuolar protein sorting 25 homolog	mammalian protein found in Homo sapiens	ELL-associated protein of 20 kDa dermal papilla-derived protein 9 vacuolar protein-sorting-associated protein 25 VPS25 ESCRT-II complex subunit VPS25

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9BRG1

part of

winged helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BRG1

ESCRT-II complex, Vps25 subunit

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BRG1

Winged helix-like DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BRG1

ESCRT-II complex, Vps25 subunit, N-terminal winged helix

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9BRG1

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9BRG1

encoded by

VPS25

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9BRG1

molecular function

protein homodimerization activity

determination method or standard

IPI

1 reference

retrieved

26 September 2017

stated in

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

protein N-terminus binding

determination method or standard

IPI

1 reference

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

structural molecule activity

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IBA

protein binding

determination method or standard

IPI

9 references

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

The Protein Network of HIV Budding

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

Next-generation sequencing to generate interactome datasets

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

Towards a proteome-scale map of the human protein–protein interaction network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

CHMP7, a novel ESCRT-III-related protein, associates with CHMP4b and functions in the endosomal sorting pathway

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

protein homodimerization activity

determination method or standard

IBA

IPI

2 references

retrieved

8 April 2019

stated in

Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IPI

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IBA

cell component

cytoplasm

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

cytosol

determination method or standard

IDA

TAS

2 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

retrieved

8 April 2019

stated in

RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

endosome

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

membrane

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

nucleoplasm

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

endosome membrane

determination method or standard

IDA

IEA

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

retrieved

8 April 2019

stated in

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

extracellular exosome

determination method or standard

IDA

3 references

retrieved

26 September 2017

stated in

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

retrieved

26 September 2017

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

retrieved

26 September 2017

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

nucleus

determination method or standard

IDA

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

retrieved

8 April 2019

stated in

Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

ESCRT II complex

determination method or standard

IDA

TAS

2 references

retrieved

26 September 2017

stated in

Membrane budding and scission by the ESCRT machinery: it's all in the neck

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

retrieved

26 September 2017

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

ESCRT II complex

determination method or standard

IBA

IDA

IEA

TAS

4 references

retrieved

8 April 2019

stated in

Membrane budding and scission by the ESCRT machinery: it's all in the neck

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IBA

extracellular exosome

determination method or standard

HDA

2 references

retrieved

8 April 2019

stated in

Large-scale proteomics and phosphoproteomics of urinary exosomes

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

HDA

retrieved

8 April 2019

stated in

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

HDA

biological process

regulation of transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

multivesicular body assembly

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Membrane budding and scission by the ESCRT machinery: it's all in the neck

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

transcription, DNA-templated

determination method or standard

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

endosomal transport

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

protein transport

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

determination method or standard

IBA

1 reference

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IBA

macroautophagy

determination method or standard

TAS

1 reference

retrieved

8 April 2019

stated in

Membrane budding and scission by the ESCRT machinery: it's all in the neck

GOA

curator

Parkinsons Disease Gene Ontology Initiative

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

TAS

negative regulation of epidermal growth factor-activated receptor activity

determination method or standard

IMP

1 reference

retrieved

8 April 2019

stated in

Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IMP

transport

determination method or standard

IEA

1 reference

retrieved

26 September 2017

stated in

GOA

curator

UniProt

UniProt protein ID

Q9BRG1

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9BRG1&geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

multivesicular body sorting pathway

determination method or standard

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9BRG1

determination method or standard

IEA

Identifiers

RefSeq protein ID

NP_115729

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

84313

UniProt protein ID

Q9BRG1

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q9BRG1

Ensembl protein ID

ENSP00000253794

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000253794

ENSP00000465798

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000465798

ENSP00000466909

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000466909

ENSP00000467225

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000467225

PDB structure ID

2ZME

1 reference

stated in

UniProt

UniProt protein ID

Q9BRG1

retrieved

4 August 2016

language of work or name

English

3CUQ

1 reference

stated in

UniProt

UniProt protein ID

Q9BRG1

retrieved

4 August 2016

language of work or name

English

3HTU

1 reference

stated in

UniProt

UniProt protein ID

Q9BRG1

retrieved

4 August 2016

language of work or name

English

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21112846&oldid=2022951165"