The ubiquitin ligase TRIM56 regulates innate immune responses to intracellular double-stranded DNA (Q24306840)

defense response to virus

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TANK-binding kinase 1

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Transmembrane protein 173

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Tripartite motif-containing 56

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Yoshiharu Matsuura

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author name string

Tetsuo Tsuchida

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Jian Zou

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Tatsuya Saitoh

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Himanshu Kumar

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Takayuki Abe

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Taro Kawai

RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway

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language of work or name

English

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publication date

24 November 2010

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765-76

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cites work

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Reconstitution of the RIG-I pathway reveals a signaling role of unanchored polyubiquitin chains in innate immunity

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Regulation of the cytosolic DNA-sensing system in innate immunity: a current view

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

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The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA

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Innate immune recognition of, and regulation by, DNA.

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response

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Recognition of microorganisms and activation of the immune response

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TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

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AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

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Regulation of the innate immune response by threonine-phosphatase of Eyes absent

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STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

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Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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A Toll-like receptor-independent antiviral response induced by double-stranded B-form DNA.

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TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

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An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

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RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate

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TRIM family proteins and their emerging roles in innate immunity

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Intracellular DNA recognition

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TRIM family proteins: retroviral restriction and antiviral defence

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Sensors of the innate immune system: their mode of action

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ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

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Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response

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Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding

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The chemotherapeutic agent DMXAA potently and specifically activates the TBK1-IRF-3 signaling axis

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HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA

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Human TRIM gene expression in response to interferons

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TRIM21 is essential to sustain IFN regulatory factor 3 activation during antiviral response

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Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages

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The C/EBP beta isoform 34-kDa LAP is responsible for NF-IL-6-mediated gene induction in activated macrophages, but is not essential for intracellular bacteria killing

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The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

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Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

21074459

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Consolidated OpenCitations Corpus – April 2017