Minerals, Metals, Mercury and Miracles - Usman
Minerals, Metals, Mercury and Miracles - Usman
Minerals, Metals, Mercury and Miracles - Usman
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Infectious Agents
Virus (Measles, HHV6, RSV) Bacteria (Streptococcus, Clostridia) Fungal (Candida)
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Aftermath
Gastrointestinal Dysfunction
Maldigestion ( Abnormal Peptides, IgG Food Sensitivities, Enzyme Deficiencies) Malabsorption ( Fat Soluble Vitamin Deficiencies, Essential Fatty Acid Deficiencies, Essential Amino Acid Deficiencies ) Dysbiosis (Aerobic and Anaerobic Bacterial, Fungal, and Viral )
Mineral Metabolism
Mineral Deficiencies
Impaired Detoxification
Methylation, Sulfation, Glutathione, Metallothionein Heavy Metal Overload Oxidative Stress
Immunological Dysregulation
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Th1 and Th2 skewing Decreased Natural Killer Cells Pro-inflammatory Cytokines Increased Autoimmune Markers
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Treatment Options Educational Therapies (ABA, AIT, RDI, Floortime) Neurofeedback Energetic Techniques (NAET, Craniosacral, Homeopathy) Dietary Interventions (Casein and Gluten Free, Specific Carbohydrate) Nutrient Therapy Heavy Metal Detoxification
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Modified Diet 40% Vitamin/Minerals 30% Food Supplements 23% Homeopathy -30% Anti- yeast 30% Prayer 16% More severe symptoms Unacceptable side effects Concern about side effects Safety of prescription drugs
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SafeMinds, Cambridge, Massachusetts, USA. Reported rates of autism have increased sharply in the United States and the United Kingdom. One possible factor underlying these increases is increased exposure to mercury through thimerosal-containing vaccines, but vaccine exposures need to be evaluated in the context of cumulative exposures during gestation and early infancy. Differential rates of postnatal mercury elimination may explain why similar gestational and infant exposures produce variable neurological effects. First baby haircut samples were obtained from 94 children diagnosed with autism using Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM IV) criteria and 45 age- and gender-matched controls. Information on diet, dental amalgam fillings, vaccine history, Rho D immunoglobulin administration, and autism symptom severity was collected through a maternal survey questionnaire and clinical observation. Hair mercury levels in the autistic group were 0.47 ppm versus 3.63 ppm in controls, a significant difference. The mothers in the autistic group had significantly higher levels of mercury exposure through Rho D immunoglobulin injections and amalgam fillings than control mothers. Within the autistic group, hair mercury levels varied significantly across mildly, moderately, and severely autistic children, with mean group levels of 0.79, 0.46, and 0.21 ppm, respectively. Hair mercury levels among controls were significantly correlated with the number of the mothers' amalgam fillings and their fish consumption as well as exposure to mercury through childhood vaccines, correlations that were absent in the autistic group. Hair excretion patterns among autistic infants were significantly reduced relative to control. These data cast doubt on the efficacy of traditional hair analysis as a measure of total mercury exposure in a subset of the population. In light of the biological plausibility of mercury's role in neurodevelopmental disorders, the present study provides further insight into one possible mechanism by which early mercury exposures could increase the risk of autism. PMID: 12933322 [PubMed - in process]
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Conclusions:
Autistics higher prenatal Hg exposure, Hg was demonstrated when chelating agents used Autistics have an inherent problem excreting heavy metals which implies a large risk of toxicity with very small exposures
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Mercury Toxicity
Genetic Susceptibility and Synergistic Effects
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There appears to be a subset of the population that can not effectively excrete mercury and are at a greater risk to exposures to mercury than are the general population. Genetic susceptibility is critical. Presence of other heavy metals, antibiotics, etc. may enhance the toxicity of thimerosal. Synergistic toxicities must be considered. Estrogen is protective against thimerosal toxicity. Testosterone increases the toxicity of thimerosal. Gender plays a role in toxicity.
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Impaired transsulfuration and oxidative stress in autism: Improvement with targeted nutritional intervention
S. Jill James, PhD.
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Sulfate
Alpha Lipoic Acid
Coenzyme A
Taurine
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Severe hyperactivity, tantrums, screaming fits Sensory - biting, spinning, light, sound, touch Socialization isolation Language - expressive delay, receptive delay Compulsive, ritualistic
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Normal range Optimal range 70 155 70 150 0.91 1.39 < 20 90 100 100-120 1.0 < 10
Plasma Zinc
(mcg/dl)
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20 200
40 70
Anju Usman, M.D.
99% of test subjects had abnormal Cu/Zn ratios (499/503) Extremely disordered levels of Cu and Zn, indicating absence of blood homeostasis for these metals in 428 subjects (85%), Moderately disordered Cu/Zn levels despite ongoing zinc therapy in 41 subjects (8%), Severe pyrrole disorder in an additional 30 subjects (6%), indicating severe zinc depletion, Only 4 of the 503 autism-spectrum patients did not exhibit a serious metal-metabolism disorder.
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Impaired production of active B vitamins Cancer Skin disorders- Acne, Psoriasis, poor wound healing
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PE: Sparse head hair Groove across nails or white spots Nasal polyps Dark skin Canker sores Acne Psoriasis Body odor Labs: Plasma zinc (<90ug/dl)
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Treat Zinc deficiency until Zinc level optimized (100mcg/dl) Induce Metallothionein (MT) production (Selenium, Glutathione) Add Manganese and Molybdenum Provide adequate amounts of vitamin B6/Magnesium Optimize Vitamin C dose Avoid Sources of Copper Tap water (Cu pipes) Swimming pools and hot tubs (Cu algaecide) Chocolate, Carob, Soy, Shellfish, Liver Avoid Red/ Yellow dyes (deplete Zn)
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Diagnosis:
Mineral-metabolism disorder (high Cu/Zn) Heavy metal overload Dysbiosis anaerobic and aerobic bad bacteria, yeast overgrowth Food sensitivities, inhalant allergies Impaired Detoxification - methylation and sulfation defects
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Diet
High Protein
High Fiber High Antioxidants
Filtered Water
Preservative-Free Organic
Environment
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Evening
Vitamin C - 300 mg Vitamin E - 200 iu Manganese - 5 mg Zinc - 60 mg
Gut
Probiotics Enzymes with DPP IV Nystatin Advanced Biocidin
TMG - 175 mg
DMAE - 40 mg Calcium/Magnesium 200/200 mg
TMG - 175 mg
SuperEPA - 500 mg Calcium/Magnesium 200/200 mg
Vancomycin
S-adenosyl methionine
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Methylcobalamin(B12) Injections
Helps pivotal step in the methylation cycle Bypasses impairments along folate pathway Methylates dopamine Shown to help cognitive ability, abstract thinking, attention, focus, awareness, language, behavior, OCD, anxiety, . Highly concentrated, injected subcutaneous in gluteal tissue, slow release, painless, no toxicity associated with high dose vitamin B12 No test for methylB12 deficiency Side effect increased energy, hyperactivity
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Case Study
Alex - age 11.5 yrs BHx: FT, NSVD, mom - many amalgams, yeast infect., fibromyalgia Med Hx: severe eczema, allergies, reflux, freq. otitis media, 11 rounds of antibiotics age 1mo 21mo., diarrhea for years followed by constipation, chemical sensitivities Dev Hx: no regression, anxiety, stims, sound sensitivity, fine and gross motor delays, major language delay, sensory issues Past Interventions: GF/CF, soy-free diet, AIT/Tomatis, DMSA, Gut Therapies, Secretin, Nutrient Therapy
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Case Study
2 yr. Diagnosed with autism, numerous antibiotics, chronic diarrhea, reflux, vomiting, played for hours with fingers 3yr. Tactile defensiveness, severe cravings for pasta, urine milky smelled like asparagus, flapping ears, hi pain tolerance, no speech, diarrhea 5yr. 4+ Casein and gluten peptides, CF/GF diet, better eye contact, decreased tactile defensiveness, appropriate response to pain, no speech, no longer craving gluten, diarrhea now constipation 6.5 yr. Treated with Nystatin, severe die-off reaction, high CD8, low NK cells and activity, high cmv titers 7yr. High CMV titer, Ganciclovir for 6 months, no change. High dose DMG, imitated animal sounds, still no speech, severe constipation, eczema 7.5 yr.RX= p5p, Mg, niacin, GSH, DMG, EPO, Flax oil, Epsom salts baths, herbalax, protein powder, mvi, nystatin, probiotics, folic acid caused yelling, screaming, and insomnia, IV Secretin times one, improved constipation for 3 weeks 8 yr. Abnormal fungal metabolites treated with uva ursi, lamisil. Hair and urine with high Hg. DMSA started. 10 yr. Chelation therapy with DMSA and ALA.
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Glutathione (IV, Transdermal, PO, nebulized, IV) Alpha Lipoic Acid (PO, Transdermal) N-Acetyl Cysteine (PO, Transdermal, IV) Homeopathics Herbals (garlic, cilantro, chlorella, spirulina) RNA Therapy
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Thank You for your children. They are all Miracles of God
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