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Kuliah Blok GI Tract-ERCP, Agustus 2010

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Endoscopic, Retrograde Cholangio Pancreatography/ERCP

Dr. Yanto Budiman, Sp.Rad., M.Kes Bagian Radiologi FK/RS Atma Jaya Jakarta

ERCP
Endoscopic, Retrograde Cholangio Pancreatography Endoscopic :use of an instrument called an endoscope - a thin, flexible tube with a tiny video camera and light on the end. Retrograde :The direction in which the endoscope is used to inject a liquid enabling X-rays to be taken of the parts of the GI tract called the bile duct system and pancreas. The process of taking these X-rays is known as cholangiopancreatography. Cholangiopancreaticography :Imaging the bile duct system, and pancreas.

Indications for imaging


Gallstones, which are trapped in the main bile duct
Blockage of the bile duct Jaundice Undiagnosed upper-abdominal pain Cancer of the bile ducts or pancreas Pancreatitis

When pancreatitis is caused by gallstones, it is necessary to remove the gallbladder. At times, an ERCP (Endoscopic Retrograde CholangioPancreatography) test is recommended. This involves passing a flexible tube through the mouth and down to the small intestine. A small catheter is then inserted into the bile duct to see if any stones are present. If so, they are then removed with the scope.

Preparations
Patients should ingest no solids for at least 6-7 hours and

no liquids for at least four hours prior to the procedure. For some procedures, topical pharyngeal anesthesia alone is sufficient, especially when the endoscopy is performed with a small diameter endoscope. For prolonged examinations, those in children, or in patients with a high degree of anxiety, rapid onset sedatives and/or analgesics are often necessary. Anticholinergics (e.g., atropine) have been given to decrease saliva, gastric secretions and motility, and reduce the likelihood of vasovagal reactions; For procedures in which paresis of gastroduodenal motility is necessary, parenteral glucagon may be useful

Basic Procedure
The throat is anesthetized with a spray or solution The endoscope is then gently inserted into the upper esophagus. The

patient breathes easily throughout the exam, with gagging rarely occurring. A thin tube is inserted through the endoscope to the main bile duct entering the duodenum. Contrast media is then injected into this bile duct and/or the pancreatic duct and x-ray films are taken. The patient lies on his or her left side and then turns onto the stomach to allow complete visualization of the ducts. If a gallstone is found, steps may be taken to remove it. If the duct has become narrowed, an incision can be made using electrocautery (electrical heat) to relieve the blockage, it is possible to widen narrowed ducts and to place small tubing, called stents, The exam takes from 20 to 40

Side Effects and Risks


A temporary, mild sore throat sometimes occurs after the

exam. Serious risks with ERCP are uncommon. One such risk is excessive bleeding, especially when electrocautery is used to open a blocked duct. In rare instances, a perforation or tear in the intestinal wall can occur. Inflammation of the pancreas also can develop. There is also a small risk of an allergic reaction to the dye, which contains iodine. Rarely, drugs used to relax the ampulla of Vater can have side effects such as nausea, dry mouth, flushing, urinary retention, rapid heart rate (sinus or supraventricular tachycardia), or a drop in blood pressure Due to the mild sedation, the patient should not drive or operate machinery for six hours following the exam.

Contrast Media

20 ml non-ionic/low-osmolality 200 mg/ml contrast media

ERCP

Magnetic resonance cholangiopancreatography (MRCP)


When compared to ERCP or PTC the accuracy is very similar. MRCP has a sensitivity and specificity of 91% and 98% respectively for choledocholithiasis . Its accuracy for benign and malignant obstruction is 90%. Does not carry the 5 - 30% failure rate associated with ERCP . It is also spares the morbidity (1-7%) and mortality (0.2-1%) of ERCP and is twice as cost effective .

The disadvantage is that it is solely a diagnostic test.


It should not be used in choledocholithiasis when there is a high likelihood of a CBD stone. In this situation ERCP would be indicated since endobiliary therapy can also be carried out. MRCP is not the initial investigation of choice in

cholecystitis as ultrasound is just as accurate and much more cost effectiv

THANK YOU

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