02 Candida Albicans
02 Candida Albicans
02 Candida Albicans
Dimorphic
Dimorphic Mold yeast
candida albicans
coccidioides immitis
Histoplasma capsulatum
• Oral biome is fighting for food and energy. Normally the good bacteria
outcompete candida and it does not flourish
• Antibiotics can kill those competing bacteria and allow the candida to get
the energy and food and flourish, causing candidiasis, oral thrush,
bilateral angular chelitis…
candidiasis
• Oral candidiasis
• Pseudomembranous candidiasis
• Angular chelitis
Treatment
• Nystatin
• amphotericin B
• fluconazole
• clotrimazole
• dimorphic
• Angular chelitis = Corners of the mouth
• Treat with nystatin or amphotericin B or fluconazole or clotrimazole
• Has a pseudocapsule
• Opportunistic infection – almost always present in mouth but not able to grow
because of the dominant bacterial flora.
• Oral candidiasis may result due depressed immune system, specifically destruction of T-
lymphocytes
• Be careful – NOT usually airborne, just always present in body, so we don’t “catch it”
• Fungus spread person to person EXCEPT candida
• More common in those with HIV/AIDS (if they ask about carcinoma in the mouth with
HIV/aids = Kaposi sarcoma)
• Can produce chlamydospores
Which of the following would most likely to be colonized after Candidiasis is more common in
scraping mucous membranes of a healthy non-diseased people with a deficiency in which
patient? cell type?
A. Cryptococcus Neoformans A. B-Cells
B. Aspergillus flavus B. T Cells
C. coccidioides immitis C. Macrophages
D. Histoplasma capsulatum D. Plasma Cells
E. Candida albicans E. Neutrophils