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Pink Illustrative Organic Biology Project Presentation

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NUCLEIC

ACIDS
: DNA AND RNA
NUCLEIC ACIDS:
• Nucleic acids are biopolymers,
macromolecules, essential to all
known forms of life.
• Are the largerst and the most complex organic
molecules. Discovered by Friedric Miescher in
1897.

•• There
NUCLEIC ACIDS:
are two types of-
• The RIBONUCLEIC ACID (RNA) and The
DEOXYRIBONUCLEIC ACID (DNA)
NUCLEIC ACIDS
CHARACTERISTICS AND FUNCTIONS
Characteristics and Functions of nucleic acids:

DNA (Deoxyribonucleic acid)

double stranded or double helix nucleic acid

located in the nucleus (particularly eukaryotes).


And are binded in the chromosome, where is stored
in the chromatin.

serves as a cellular library (stores genetic


information).
Characteristics and Functions of nucleic acids:

RNA (Ribonucleic acid)


single stranded nucleic acid
mostly found outside of the nucleus

functions in regulating the expression of dna information storage, in the


protein synthesis process.

• diff types:
- ribosomal rna (Rrna). - messenger rna (Mrna)
.- transfer rna (Trna).
NUCLEIC ACIDS
COMPOSITION
COMPOSED OF :
01 02 03

•Polypeptides (are the building • Nucleic acids are substances with • ( DNA AND RNA are both
blocks of nucleic acids) high molecular weight ranging polymers )- a long molecule
from 1,286 to 3,000,000. made up of tiny units called
- Peptides are short chains of monomers.
amino acids linked by peptide Made up of CARBON, • The monomers that make up
bonds. HYDROGEN, OXYGEN, dna and rna are:
NITROGEN, AND
NUCLEOTIDES
PHOSPHORUS.
• Nitrogen - 15-16%
NUCLEIC ACIDS
: NUCLEOTIDES
NUCLEOTIDES
NUCLEOTIDES -linked together by
dehydration synthesis or polymerization
reactions, between the sugar of one
nucleotide and the phosphate group of
another.
• NUCLEOTIDES has its basic parts, these are:

- Heterocyclic Base / Nitrogenous Base


- Phosphate group
- Pentose sugar ( 5 carbon sugar )
NUCLEOTIDES: Heterocyclic Base / Nitrogenous
Base
COMMON PAIRS:
DNA - A (adenine) : T(thymine),
G (guanine) :(cytosine) C,

• a DNA molecule contains millions of BASE


PAIRS and they are anti-parallel to each other:
One runs from 5' to 3' and the other is the
opposite, from 3' to 5'.

• an AT pair makes TWO hydrogen bonds.


• a CG pair makes three hydrogen bonds.
NUCLEOTIDES: Heterocyclic Base / Nitrogenous
Base
COMMON PAIRS:
RNA - A (adenine) : U (uracil)
G (guanine) : (cytosine) C

Meaniwhile in RNA: G to C, instead of A to T, A


to U is used as base pairs. T (thymine) is
replaced by U (uracil) when it comes to RNA.

KEY: U (URACIL) REPLACES T


(THYMINE)
PURINES AND PYRIMIDINES Nitrogenous
bases are
divided into
03 2 types:
PURINES
AND
to determine
PYRAMIDI
NES.and
purines
pyramidines,
they differ and
depend on the
number of ring
they have.
NUCLEOTIDES basic parts:
phosphate group

-Phosphate, chemical formula PO43-, is a chemical


compound made up of one phosphorus and four
oxygen atoms. When it is attached to a molecule
containing carbon, it is called a phosphate group. It
is found in the genetic material DNA and RNA.

(also in molecules such as adenosine triphosphate


(ATP) that provide energy to cells)
NUCLEOTIDES BASIC
PARTS: PENTOSE SUGAR
( a pentose is a monosaccharide with five carbon atoms)

DIFFERENCE IN DNA AND RNA’S PENTOSE SUGAR:


In RNA, the carbon at the C-2 position is attached to a
hydroxyl (OH) group. In DNA, the carbon at the C-2 does
not contain this hydroxyl group; rather it is replaced by a
hydrogen (H) atom.
(That is why..)

In RNA, the sugar is RIBOSE, whereas in DNA Nucleotide


NUCLEIC ACIDS
DNA AND RNA'S FUNCTION AND
PROCESS:
NUCLEOTIDES: DNA
REPLICATION
DNA replication is the process by which the genome’s DNA is copied in cells. Before a cell
divides, it must first copy (or replicate) its entire genome so that each resulting daughter cell
ends up with its own complete genome.

Process: DNA
REPLICATION:
Step 1: Replication Fork Formation. Before DNA can be
replicated, the double stranded molecule must be “unzipped”
into two single strands. ...
Step 2: Primer Binding. The leading strand is the simplest to
replicate.
DNA REPLICATION
PROCESS:
PROTEIN SYNTHESIS
: Mrna, Trna, Rrna

2 Stages: Protein synthesis


• Transcription • Initiation
• Translation • Elongation
• Termination
P
r
o S
t y
e n
i t
n h
e
s
i
Thank you!
EXTRA INFORMATION:

• The combination of a base and sugar is


called a NUCLEOSIDE.

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