Review
Review
Review
• Hydrogen bonds
• Van der Waals forces
• Ionic interactions
• Hydrophobic
interactions
None of these forces are strong enough to bind free atoms together.
(typically range from 4 to 30 kJ/mol)
Hydrogen bonds (H bonds)
Hydrogen bonds Form between a hydrogen and a second electronegative
atom
Strength: 12~30 kJ/mol ; Distance: 0.3 nm
Van der Waals forces are the result of induced electrical interactions
between closely approaching atoms or molecules as their negatively
charged electron clouds fluctuate instantaneously in time.
Strength depends on the relative size of the atoms or molecules and the
distance between two molecules: The greater the area, the stronger the
interaction.
The sum of many such interactions within a macromolecule or between
molecules can be substantial (accumulated).
Ionic interactions