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Oogenesis

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AL-Zaiem AL-Azhary University

Fauclty of Medicine
Human Anatomy MSC. Program
General Embryology

OOGENESIS
Dr. Israa Ahmed Ali
Faculty of Dentistry, International University of Africa, Sudan
Contents

Gametogenesis

Oogenesis

Hormonal regulation

Clinical relevance

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Learning outcomes

Discuses the clinical


relevance of oogenesis

Explain the hormonal


regulation of oogenesis
Identify the key events and
features along the timeline
of oogenesis
Address the two
processes of oogenesis
Outline the purpose of
oogenesis

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Gametogenesis
Definition
 The process of production of mature gamets (sperms ,
ovum) from the gonads .

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Gametogenesis

Purpose

 To produce haploid daughter cells (reduce the


chromosomes numbers by its half) .

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Oogenesis
Definition

 The process of production mature haploid


ovum ready for fertilization.
 Mostly takes place in the cortex of the ovaries.

Timing

 From the 12th week IU to menopause.


 During the fertile period of a female, one mature
ovum is developed every 28 days.

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Oogenesis
The ovaries

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Oogenesis

Maturatio
n
of
follicular Maturation
cells Of
the 1ry oocyte

The two process


Of
oogenesis

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Oogenesis

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Oogenesis
Key events along the timeline of
oogenesis

Birth Ovulation
Diffrintion of • .Follicular growth • Occurs in uterine •
One follicle • .tube
stem cell to .Primary follicles • Graffin follicle •
Completes Meiosis-2 •
oogonum .1ry oocytes • .meiosis-1 .rupture .completed
Meiosis-1 paused at • .2ry oocytes •
Meiosis-2 paused • Fertilizatio
12th M IU .pro-phase
Puberty .at metaphase n

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Oogenesis

No ovulation occurs during


pregnancy, what is the reason in
your opinion?

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Oogenesis
Hormonal regulation
of
oogenesis

PROGESTRONE
ESTROGEN

FSH
LH

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Oogenesis
Clinical relevance
of
oogenesis

Age Chemotherapy
& &
Infertility Radiotherapy

Oral
contraceptives

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Further readings

 Ovarian cycle.

 Uterine cycle (menstrual cycle).

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References

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 Thank you 

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