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Metoprolol Drug Prsentation: By, Rachel - J BSC Nursing 2 Year College of Nursing, Christian Fellowship Hospital

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METOPROLOL

DRUG PRSENTATION

By,
Rachel . J
BSc NURSING 2nd year
College of nursing ,
Christian fellowship hospital .
CONTENT :
 Drug Information
 Name of Drug
 Generic Name
 Chemical Name
 Trade Name
 Mode of Action
 Drug absorption and Elimination
 Route of Administration.
CONTENT :
 Available forms and dosages
 Cost of drug
 Side Effects (System wise)
 Nursing intervention (Before, During , Post
administration care)
 Antidote (if available)
 Patient and family education
 Reference.
INTRODUCTION :
METOPROLOL
 Metoprolol, sold under the brand name
Lopressor, among others, is a selective β₁
receptor blocker medication. It is used to
treat high blood pressure, chest pain due
to poor blood flow to the heart, and a
number of conditions involving an
abnormally fast heart rate.
DRUG INFORMATION :

Name of Drug : METOPROLOL

Generic Name : METOPROLOL

Chemical Name:METOPROLOL
SUCCINATE

Trade Name : MAGISTRA C & C


MODE OF ACTION :

 It lowers the blood pressure by beta-


blocking effects .

 It also blocks beta 2 – adrenergenic


receptors in bronchial , Vascular
smooth muscle only at high doses,
Negative chronotropic effect .
DRUG ABSORPTION :
 When metoprolol is administered orally , it is almost
completely absorbed in the gastrointestinal tract
.
 The maximum serum concentration is achieved 20
minutes after intravenous administration and 1-2
hours after oral administration .
 The bioavailability of metoprolol is of 100% when
administered intravenously and when administered
orally it presents about 50% for the tartarate
derivative and 40 % for the succinate derivative .
 The absorption of metoprolol in the form of the
tartarate derivative is increased by the concomitant
administration of food .
ELIMINATION :

 Metoprolol is mainly excreted via the


kidneys.

 Frrom the eliminated dose , less than 5%


is recovered unchanged .
ROUTE OF ADMINISTRATION :

 ORAL

 INTRAVENOUS
AVAILABLE FORMS :

 Metoprolol is available in the TABLET


form
AVAILABLE DOSES :
 Metoprolol is available in the following
doses:

 25 mg
 37.5 mg
 50 mg
 70 mg
 100 mg
COST OF THE DRUG :

 Metoprolol is 169. 18 RUPEES in India


SIDE EFFECTS -
BASED ON SYSTEM WISE :
CNS :
 INSOMNIA
 DIZZINESS
 MENTAL CHANGES
 HALLUCINATIONS
 DEPRESSIONS
 ANXIETY
 HEADACHES.
CV :
 CHF
 PALPITATIONS
 DYSRHYTHMIAS
 CARDIAC OUTPUT
 AV BLOCK
 HYPOTENSION
 BRADYCARDIA
EENT :

 SORE THROAT
 DRY BURNING EYES
GI :
 NAUSEA
 VOMITING
 COLLITIS
 CRAMPS
 DIARRHEA
 FLATULENCE
 DRY MOUTH
 HICCUPS
HEMA :

 AGRANULOCYTOSIS
 EOSINOPHILIA
 THROMBOCYTOPENIC PURPURA
INTEGUMENTARY :
 RASHES
 PURPURA
 ALOPECIA
 DRY SKIN
 URTICARIA
 PRURITUS
RESPIRATORY :

 BRONCHOSPASM
 DYSPNEA
 WHEEZING
NURSING MANAGEMENT –
BEFORE CARE :
 Monitor the blood pressure , ECG nad pulse
frequently during dose adjustments and
periodically during therapy .
 Assess for edema , baselines in renal.
 Monitor frequency of prescription refills to
determine compliance .
 Assess for dyspnea, input and output also.
 Monitor vital signs and ECG every 5 – 15
minutes during and for several hours after
parenteral administration .
 Check the weight daily .
DURING CARE :
 Give the medication as per doctor’s order.

 Give the medicine along with a meal or just


after a meal.

 Administer medication at same time every


day.

 Teach patient about to swallow the capsule


as a whole and do not crush , break, or open
it.
CONTINUE-
 Measure liquid medicine carefully by using
the medicine – dose measuring device .

 Monitor blood pressure at frequent times of


intervals .

 Store the medicine at room temperature


away from the moist and heat .
POST CARE :
 Prior to dose , check the apical and
peripheral pulses

 After administering medication to the


patient monitor blood pressure, pulmonary
wedge pressure, and cardiac rhythm and
conduction

 Monitor cardiovascular system : BP , HR, and


edema .
ANTIDOTE :
 There is no specific antidote . In general ,
patients with acute or recent myocardial
infarction may be more haemodynamically
unstable than other patients and should be
treated accordingly .
PATIENT AND FAMILY
EDUCATION :
 Teach patient not to use OTC products
containing alpha-adrenergic stimulants ( such as
nasal decongestants, cold preparations) , to
avoid alcohol, smoking and to socium to limit
intake as prescribed .

 Teach patient how to take pulse and bp at


home. Advise when to notify the presciber .

 Instruct patient to comply with weight control,


dietary adjustments, modified exercise
program .
CONTINUE-
 Tell the patient to carry or wear the emergency ID to
identify product being taken , allergies. Tell patient
product controls symptoms but does not cure .

 Caution patient to avoid hazardous activities if


dizziness, drowsiness is present , to avoid driving
until product response is unknown .

 Teach patient to report symptoms of CHF, difficulty


in breathing , especially with excertion or lying down
, night cough , swelling of extremities or bradycardia,
dizziness, confusion , derpression , fever, decreased
vision.
CONTINUE -
 Teach patient to take product as prescribed
not to double doses or skip doses, take any
missed doses as soon as remembered if
atleast 4 hour until next dose.

 Advise to monitor blood glucose closely if


diabetic .

 Advise to report Raynaud’s symptoms.


REFERENCE :
 BOOKS
 AUTHOR : Linda skidmore
 YEAR : 2011
 TITLE : Mosby drug guide for nursing
student
 EDITION : 11th edition
 PUBLISHER NAME : Elsevier
 PAGE NO. : 684
ONLINE RESOURCES :
 Author : Sanjai sinha , MD
 DOCUMENT TITLE : Metoprolol
 WEBpage name : DRUGS. COM
( drugs.com/metoprolol.html)

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