REVIEW QUESTIONS For MIDTERMS
REVIEW QUESTIONS For MIDTERMS
REVIEW QUESTIONS For MIDTERMS
A- PROTECTIVE ANTIGEN
3. A young man sustains major soft tissue injury and open- fractures of
his right leg after a motocyle accident. One day later, he has a temp of
38 deg.
E- CLOSTRIDIUM PERFRINGENS
D- 6 WEEKS
A- Fried rice
7. Tetanus toxin (tetanospasmin) diffuses to terminals of inhitory cells
in the spinal cord and brainstem and blocks which of the following?
10. A 67 year old man had a surgery for a ruptured sigmoid colon
diverticulum wit an abscess was drained.
C- CLOSTRIDIUM PERFRINGENS TOXIN
11. Infant botulinum has been associated with all of the ff except?
B- CLOSTRIDIUM SEPTICUM
12. Which of the ff food items is most frequently associated with infant
botulism?
D- HONEY
• 13. All of the ff are properties characteristic of Bacils anthracis,
expect?
D- NORCARDIA FARCINICA
B- Trimethoprim-sulfamethozaxole
3. It is practicularly difficult to differentiate Erysipelothrix rhusiopathiae
from
E- Lactobacillus species
A- NOCARDIA BRASILIENSIS
9. Skin diptheria as occurs in children in tropical areas typically
B- ERYSIPELOTHRIX RHUSIOPATHIAE
11. A biochemical reaction that is useful identification of the causitive
agent of the infection in question 10 as
E- PRODUCTION OF H2S
A- CORYNEBACTERIUM UREALYTICUM
Page 206- Stapyloccoci
1. A 54 year old woman develops a right should abcess with strain of
Staphylococcus aureus that is resistant to nafcillin.
2. An 11 year old boy develops a mild fever and pain in his upper arm.
E- CATALASE POSITIVE
3. A 36 year old male patient has an abscess with the strain of S.
aureus that is b-lactamase positive. This indicates that the organism is
resistanty to
6. The exfoliative toxins, TSST-1, and the enterotoxins are all superantigens.
E- The S epidermidis organisms are likely to bein a biofilm obn the central
venous catheter surface.
8. A 65 year old man develops an abcess on the back of his neck. Culture
yields S aureus.
C- S aureus
11. Which of the following statements regarding the role of protein A in
the pathogenesis of infection
A- Staphylococcus intermedius
13. All of the following statements regarding Panton-Valentine leukocidin are
correct except?
14. Which of the following statements best describe the function of the
accessory gene?
E- ESCHERICHIA COLI
2. A 27 year old woman is admitted to the hospital because of fever,
with increasing anorexia, headache, weakness and altered mental
status of 2 days duration. She works for an airline. Her temp is 39, heart
rate is 68, blood pressure is 120/80 Hg. She knows she is and where she
is but does not know the date.
4. A 37 year old women with historyb of urinary tract infection comes to the
emergency department with burning on urination along with frequency and
urgency. She says her urine smells like ammonia.
B- PROTEUS MIRABILIS
5. An 18 year old student has abdominal cramps and diarrhea. A plate
of MacConkey agar is inoculated and grows gram negative rods. Triple
sugar ion is used for the isolates for salmonellae and shigella.
E- PROTEUS
8. A 4 year old boy from Kansas City who recently started attending preschool
brought to his pediatrician for diarrheal illness by fever to 38.2 Which of the
foolowing is the most likely pathogen causing the llness?
C- SHIGELLA SONNEI
9. A 5 year old girl attended a party at local fast food restaurant. About 48 hrs, se
developed cramping abdominal pain and low grade fever. a serum 8 mg ./dl. What
most likely pathogen causing child?
10. a 55 year old homeless man wth alcolohism presents severe multilobar
pneumonia. The organism is a lac tose fermenter MacConkey agar and very much
mucoid.
D- KLEBSIELLA PNEUMONIAE
11. Which of the following statements reagarding o antigen is correct/
12. Which of the following test methods is the least sensitive procedure
for diagnosis of colitis caused by Shiga toxin- producing E COLI?
E- ENTROAGGREGATIVE E COLI
14. Heat- labile toxin of ETEC acts by which of the following mechanism?
E- STENOTROPHOMONAS MALTOPHILIA
3. This gram negative bacillus, which is oxidase positive and does not ferment
carbohydrates
D- EIKENELLA CORRODENS
4. A 17 year old girl with cystic fibrosis has a slight increase in her frequently
cough and production of mucoid sputum. A sputum specimen is obtained and
plated on routine cultre media.
B- PSEUDOMONAS AEROGINOSA
5. The sputum from a 17 year old patient with cystic fibrosis in question
4 also plated on mannitol salt agar, which turns
D- STAPHYLOCOCCUS AUREUS
6. The sputum from a 17 year old patient with cystic fibrosis also plated
on a colistin-containing agar. After 72 hours of incubation, the colistin-
containing agar grows.
B- BURKHOLDERIA CEPACIA
7. When Burkholderia cepacia complex organism is isolated from a patients
with cystic fibrosis, great care must.
A- PSEUDOMONAS AEROGINOSA
D- PYOVERDIN
11. Burkholderia cepacia is infrequently found in or
A- SWIMMING POOL
E- KINGELLA KINGAE
15. A 30 year old man , a dog owner presents a fever of 39
hypotension and early signs of dismented intravascular coagulation.
Sepsis is suspected. The most likely pathogen is
B- CAPNOCYTOPHAGA CANIMORSUS
PAGE 263- Vibrios, Camylobacters,
Helicobacter and Associated Bacteria
1. Long term carriage and shedding is most likely to occur after
gastrointestinal infection With which of the following?
E- SALMONELLA TYPHI
2. A 63 year old man visited his fav oyster restaurant. He ate 2 dozen of
oyster/. Two days later, he was admitted to the hospital because of absurpt
onset of chills. A microorganism of major concern for this patient is:
A- VIBRIO VULNIFICUS
3. A 10 year old boy was playing in a slowly moving stream which he cut his foot
on a shrap object. Three days later he was brought to the emergency
department because of the pain.
C- AEROMONAS HYDROPHILA
4. A family of four persons ate a meal that included undercooked chicken. Within
3 days, three members develpoed an illness characterized by fever, headache,
myalgia. Which of the following culture was most likely used to islate C jejun?
A- SALMONELLA TYPHI
6. During the El Nino years in the mid 90, the waters of the Puget
sounds between washington state and british columbia. The micro
oraganism of concern is:
D- VIBRIO PARAHAEMOLYTICUS
7. A patient presents to the emergency dept. with nonbloddy diarrhea
for 12 hrs. The patient lives and has not recently traveled out of the
area. Which of the folloswing is unlikely the cause?
D- VIBRIO CHOLERAE
8. An 18 year old woman in rural Bangladesh develops profuse 8L/d
diarrhea. She has no symptoms other than the diarrhea and the
manifestation of the fluids and electrolytes.
D- SHIGELLA DYSENTERIAE
9. Age and geography are major factors in the prevalence of colonization by
Helicobacter pylori. In the developing countries, the prevalence of colonization
may be greater than 80% in adults.
D- 40-60%
10. A 59 year old man comes to the emergency dept in the afternoon because of
acute swelling and pain in his right leg. Earlier that morning, he had been working
on a small sport fishing boat in an estuary.Near the wound , bullae were forming-
the largest approx 2.5 cm in diameter.
E- VIBRIO VULNIFICUS
11. The vibrio cholerae factor responsible for diarrhea is a toxin that
D- BRUCELLA SPECIES
2. After the culture test in question 1 turned positive, additional history was obtained.
Approx 4 weeks before the onset of her knee pain.
E- FRANCISELLA TULARENSIS
4. An 18 year old boy has been playing with ach
A- BRUCELLA SPECIES
C- AGGREGATIBACTER APHROPHILUS
A- TULARENSIS
B- BORDETELLA PERTUSSIS
C- BORDETELLA PERTUSSIS
E-STREPTOMYCIN
3. Yersinia pestis entered North America through SAN fRANCISCO in the
1890s, carried by rats on ships that had sailed from HK, where a plague
epidemic occurred.
C- STREPTOCOCCUS PYOGENES
5. An 8 year old boy was bitten by a stray cat. Two days later, the wound was
red and swollen and drained purulent fluid. Pasteurel multocida was cultured
from the wound. the drug?
D- PENICILLIN G
E- DOXYCYCLINE
7. In a patient who has the bubonic form of plague, all the following
specimens are acceptable except?
10. Which of the following Pasteurella species has been associated with
infections of the female genital tract and of the newborn?
D- PASTEURELLA BETTYAE
11. Optimum recovery of Yersinia enterecolitica from the stools of patients
ith gastrointestinal requires which of the following specialized media?
A- CEFSULODIN-IRGASAN-NOVOBIOCIN AGAR
D- YERSINIA ENTEROCOLITICA
13. A 25 year old graduate student is rushed to the operating room for
fever, acute abdominal pain and leukocytosis suggestive of acute
appendicitis. During the surgery, the appendix appears normal,
2. A 19 year old man presented to the clinic with a urethral discharge for the
past 24 hrs. Which of the following statements about these antimicrobial
resistance factor?
A- B-lactamase production and high-level resistance to tetracycline are both
mediated by genes on plasmid.
3. A 6 year old boy develops a fever and headache. He is taken to the
emergency dept, where he is noted to have a stiff neck, suggesting
meningeal irritation.
B- PILI (FIMBRIAE)
10. A 60 year old man with severe chronic lung disease presents with
fever, cough productive of purulent sputum and worsening hypoxemia.
C- MORAXELLA CATARRHALIS
11. One major advantage of the conjugate meningococcal vaccines
compared with the polysaccharides vaccines?
12. A 25- year-old woman presents with septic arthritis of the knee. The
fluid aspirate grows a gram-negative diplococcus
D- Neisseria gonorrhoeae
13. All of the following are virulence factors associated with N
gonorrhoeae except.
A- TRUE
15. A useful test to differentiate Moraxella catarrhalis from saprophytic
neisseriae in the respiratory samples is
A- BUTYRATE ESTERASE
page 302- Infections caused by anaerobic
bacteria
1. A 55 year old man visits his physian complaining of a severe cough and
production of purulent sutum. His breath h a very unpleasant fetid odor.
4. An 18 year old man develops fever with the pain in the right
lower quadrant of his abdomen.
B- CAPSULE
5. Infection caused by bacteroides species can be treated with all of
the following antibiotics except?
D- PENICILLIN
A- Fusobacterium necrophorum
7. Which of the following statements regarding Lactobacilli is correct?
E- PENICILLIN
B- LUMPY Jaw
11. All of the following statements regarding anaerobes are true except.
E- FUSOBACTERIUM NECROPHORUM
13. Definitive identification of an anaerobe is likely best accomplished
by
D- ACTINOMYCES ISRAELII
15. The recommended treatment in the non-allergic patient for the
condition caused by the organism in question 14?
A- AMPICILLIN
PAGE 310- Legionellae, bartonella and unsual
bacterial pathogens.
1. Humans become infected with Legionella pneumophilia by
B- STEPTOBACILLUS MONILIFORMIS
3. A 70 year old man presents with bilateral pneumonia. His legionella urinary
antigen test result positive. Which of the ff is likely?
4. A 70 year old man comes to the emergency dept. feeling feverish and really
tired. He has chronic cigarette cough, but this has dramatically increased in
the past week.
12. Which of the following best represents the role of the Mip protein in
Legionella pathogenesis?
B- FALSE
B- MYCOBACTERIUM KANSASII
A- HIV/AIDS
B- MYCOBACTERIUM CHELONAE
E- They are used as alternatives to the tuberculin skin test to evaluate for
latent tuberculosis.
B- Mycobacterium mucogenicum
D- MYCOBACTERIUM NONCHROMOGENICUM
PAGE 345- Mycoplasmas and Cell wall-
defecive bacteria
PAGE 338- Spirochetes and other spiral
microorganisms
PAGE 356- Rickettsia and related genera
PAGE 368- Chlamydia spp.
PAGE 403- Antimicrobial Chemotherapy
PAGE 429- General properties of viruses