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    Glp-1 Receptor Agonists (GLP-1 RA) : Presented By: Nermeen S. Esa (Clinical Pharmacist)

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    Parishan Saeed
    The document discusses GLP-1 receptor agonists (GLP-1 RAs) for the treatment of type 2 diabetes. It notes that the 2020 ADA guidelines recommend GLP-1 RAs to help lower HbA1c and prevent hypoglycemia, as well as to reduce cardiovascular risk for patients not meeting treatment goals or who have existing heart or kidney conditions. The document covers the mechanism of action, classifications, dosing, administration, and side effects of GLP-1 RAs.

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    Glp-1 Receptor Agonists (GLP-1 RA) : Presented By: Nermeen S. Esa (Clinical Pharmacist)

    Uploaded by

    Parishan Saeed
    21 views10 pages
    The document discusses GLP-1 receptor agonists (GLP-1 RAs) for the treatment of type 2 diabetes. It notes that the 2020 ADA guidelines recommend GLP-1 RAs to help lower HbA1c and prevent hypoglycemia, as well as to reduce cardiovascular risk for patients not meeting treatment goals or who have existing heart or kidney conditions. The document covers the mechanism of action, classifications, dosing, administration, and side effects of GLP-1 RAs.

    Original Description:

    GLP-1 receptor Agonists

    Original Title

    GLP-1 receptor Agonists

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    The document discusses GLP-1 receptor agonists (GLP-1 RAs) for the treatment of type 2 diabetes. It notes that the 2020 ADA guidelines recommend GLP-1 RAs to help lower HbA1c and prevent hypoglycemia, as well as to reduce cardiovascular risk for patients not meeting treatment goals or who have existing heart or kidney conditions. The document covers the mechanism of action, classifications, dosing, administration, and side effects of GLP-1 RAs.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    21 views10 pages

    Glp-1 Receptor Agonists (GLP-1 RA) : Presented By: Nermeen S. Esa (Clinical Pharmacist)

    Uploaded by

    Parishan Saeed
    The document discusses GLP-1 receptor agonists (GLP-1 RAs) for the treatment of type 2 diabetes. It notes that the 2020 ADA guidelines recommend GLP-1 RAs to help lower HbA1c and prevent hypoglycemia, as well as to reduce cardiovascular risk for patients not meeting treatment goals or who have existing heart or kidney conditions. The document covers the mechanism of action, classifications, dosing, administration, and side effects of GLP-1 RAs.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 10

    GLP-1 RECEPTOR AGONISTS

    (GLP-1 RA)
    P R E S E N T E D B Y:
    NERMEEN S. ESA (CLINICAL PHARMACIST)
    BACKGROUND

    • The advancement in the treatment of T2DM put in account


    cardiovascular disease prevention in addition to HbA1C lowering
    efficacy and hypoglycemic prevention.
    • ADA 2020 guideline recommend GLP-1 RA as intensification of
    treatment for patients with type 2 diabetes not meeting treatment
    goals.
    • And also recommend it among patients with type 2 diabetes who have
    established atherosclerotic cardiovascular disease or have indicators of
    high risk, established kidney disease, or heart failure, as part of the
    glucose-lowering regimen independent of HbA1C and in consideration
    FIGURE: TREATMENT ALGORITHM IN PATIENTS WITH TYPE 2
    DIABETES MELLITUS AND ATHEROSCLEROTIC CARDIOVASCULAR
    DISEASE, OR ...
    MECHANISM OF ACTION
    CLASSIFICATION
    DOSE & ADMINISTRATION
    RENAL DOSE ADUJUSMENT
    CONTRAINDICATION & WARNINGS

    • Personal or family history of medullary thyroid carcinoma


    • Multiple endocrine neoplasia syndrome type 2
    • History of pancreatitis
    • Patients with gastroparesis or severe gastroesophageal reflux
    disease
    SIDE EFFECTS

    • diarrhoea
    • nausea
    • vomiting
    • headaches
    • dizziness
    • increased sweating
    • indigestion
    • constipation
    • loss of appetite
    THANKS

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