BOTOX
BOTOX
BOTOX
TOXIN [BTX] OR
[BONTX]
{ M.GOMATHI
CRRI
DEPARTMENT OF OMFS
INTRODUCTION
clostridium botulinum
contaminated food
wound infection
BONT – 7 NEUROTOXINS
TYPE A, B ,C [C1,C2] , D ,E ,F ,G
antigenitically and serologically distinct but structurally
similar
NEUROLOGICAL DISORDERS
cervical dystonia
blepharospasm
oromandibular dystonia
hemifacial spasm
spasticity
chronic migraine
DISORDERS OF SECRETION
hyperhidrosis
Sialorrhea
OPTHALMOLOGICAL DISORDERS
Strabismus
Dry eye disease
GASTROINTESTINAL DISORDERS
achalasia
HEMIFACIAL SPASM
Caused by abberant artery abutting the facial nerve.
Evidance
drug’.
it has been sucessfully used in an ever growing list of neurological and non
neurological disorders.
Long term studies in some conditions have confirmed its saftey and efficacy.
further research still need to be carried out to clarify its efficacy in other
conditions.