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Dr. Nur Asni-Uterine Subinvolusion

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Dr. St.

Nur Asni, SpOG


BAGIAN OBSTETRI DAN GINEKOLOGI
FAKULTAS KEDOKTERAN UNIVERSITAS HASANUDDIN
SUBINVOLUTION OF THE
UTERUS

The major cause of secondary


postpartumhemorrhage
SUBINVOLUTION OF THE UTERUS
delayed involution of the uterus

results in failure of obliteration of blood


vessels at the placental site

leading to prolonged bleeding


Typically 1-2 weeks after delivery,
up to 6 weeks PP
Differential DX of increased lochia
Sloughing of placental eschar (7-14 days)
Retained placental tissue
Endometritis
Coagulopathy
Subinvolution of uterus/placental site
idiopathic, fibroids
Recurrent clots a red flag
Blood on foot sign
Approach to persistent lochia:
?symptoms/signs anemia
?symptoms/signs endometritis
Pelvic exam
CBC, INR/PT/PTT
Pelvic U/S
Uterine involution
The two main causes are
DIFFERENTIATION BETWEEN THE
TWO CAUSES IS OFTEN DIFFICULT

BOTH CONDITIONS MAY


CO-EXIST.
Ascending polymicrobial infection
Can lead to Sepsis!
Significant source of mat. morbidity and
mortality (3/100 000 deliveries)
Symptoms: F/C, abdominal pain, malaise,
+/- foul discharge, increased lochia

Physical exam: VS, respiratory, breasts, abdomen,


perineum

Signs: look weak and ill


febrile, tachycardic,
fundal/abdominal tenderness
poorly contracted uterus
Endometritis usually follows
Blood/tissue from placental site
Normal is:
Initial lochia rubra (days)
Lochia serosa: red-brownish, watery (1-2 weeks)
Lochia Alba: lighter, more mucus

Typically lochia: 5 weeks, intermittent bursts


-15% of women > 6 weeks
RETAINED PLACENTAL TISSUE
more common in

a previous history of retained placenta


OR
if there were concerns of incomplete
placenta and/or membranes.
Fever in postpartum patient within 10 days
of delivery is a medical emergency.
Refer urgently to hospital

> 7 daysconsider Chlamydia


Tx: IV antibiotics (Clindamycin and
Gentamicin +/- ampicillin)
B/P and HR
Diastolic BP 110 refer to hospital
Distolic BP 90 x 2 r/a in 1 week
PIH B/W
Diastolic BP < 90 x 2 no TX

If history indicates:
weight
Breast exam
Signs of hyper-/hypothyroid disorder
Offer to all asymptomatic women
Advise if hx perineal tear/episiotomy
Absolute must:
persistent lochia
abnormal discharge
incontinence
repeat Pap smear needed
Considering IUDneed swabs + uterine position
Initial
management should include
RESUSCITATION

Use UTEROTONIC AGENTS

Administer ANTIBIOTICS

Consider SURGICAL EVACUATION OF THE


UTERUS
Early recognition of PPH is a very important
factor in management.

An established plan of action for the


management of PPH is of great value when
the preventative measures have failed.
MANAGEMENT - ABCS
talk to and observe patient
large bore IV access (16
gauge)
crystalloid - lots!
CBC
cross-match and type
get HELP!
AIRWAY
Management - Oxytocin
5 units IV bolus
20 units per L N/S IV wide open
10 units intramyometrial given
transabdominally
Management - Uterotonics
Ergotamine - caution in
hypertension
0.25 mg IM or 0.125 mg IV
maximum dose 1.25 mg
misoprostol)- caution in asthma
400 mg pr or po
VAGINAL DELIVERY - mild ENDOMETRITIS:
Single broad spectrum antibiotic (eg.
Ampicillin 1 g IV q6h OR orally)

if CESAREAN SECTION:
Metronidazole 500 mg q8h + Cefotaxim 2g
q6h
OR
Aminoglycoside (Gentamycin) 60-100 mg q8h +
Clindamycin 900 mg q8h
if IV antibiotics used, continue for 48
hours after fever has stopped.
if fever continues and aminoglycoside-
clindamycin combination was used,
add penicillin (5M units q6h) to cover
enterococci
PO antibiotics should be used for 5
days
The more antibiotics used, the higher
the chance of necrotizing colitis

Antibiotics do appear in breast milk


but in most cases are not significant
(avoid tetracyclines)

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