Heparin is an anticoagulant used to treat acute and chronic consumption coagulopathies and prevent clotting during surgery. It works by potentiating the inhibitory effect of antithrombin on factor Xa and thrombin. Common side effects include bleeding, hematomas, nosebleeds, and alopecia with long term use. Nurses monitor patients for signs of bleeding and thrombosis and educate them on reporting symptoms and avoiding certain medications and activities while on heparin therapy.
Heparin is an anticoagulant used to treat acute and chronic consumption coagulopathies and prevent clotting during surgery. It works by potentiating the inhibitory effect of antithrombin on factor Xa and thrombin. Common side effects include bleeding, hematomas, nosebleeds, and alopecia with long term use. Nurses monitor patients for signs of bleeding and thrombosis and educate them on reporting symptoms and avoiding certain medications and activities while on heparin therapy.
Heparin is an anticoagulant used to treat acute and chronic consumption coagulopathies and prevent clotting during surgery. It works by potentiating the inhibitory effect of antithrombin on factor Xa and thrombin. Common side effects include bleeding, hematomas, nosebleeds, and alopecia with long term use. Nurses monitor patients for signs of bleeding and thrombosis and educate them on reporting symptoms and avoiding certain medications and activities while on heparin therapy.
Heparin is an anticoagulant used to treat acute and chronic consumption coagulopathies and prevent clotting during surgery. It works by potentiating the inhibitory effect of antithrombin on factor Xa and thrombin. Common side effects include bleeding, hematomas, nosebleeds, and alopecia with long term use. Nurses monitor patients for signs of bleeding and thrombosis and educate them on reporting symptoms and avoiding certain medications and activities while on heparin therapy.
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DRUG DRUG INDICATION MODE OF COMMON ADVERSE TOXICITY ANTIDOTE NURSING
CLASS ACTION/ DOSAGE/FORM/ EFFECT LEVEL AND RESPONSIBILITY
PHARMACOKI ROUTE/TIMING SIGNS AND NETICS SYMPTOMS Generic Anti o Treatment of Potentiates 50units IV GI: drug- Nosebleeds Protamine o Assess for signs of bleeding Name: thrombotics acute and the inhibitory daily induced blood in sulfate and hemorrhage (bleeding HEPARIN Anticoagulants chronic consum effect of hepatitis. urine or gums; nosebleed; unusual ption coagulopa antithrombin Recommendation tarry bruising; black, tarry stools; thies on factor Xa Dose: Derm: alopecia stools may hematuria; fall in hematocrit Brand and thrombin Line Flushing (long-term be noted as (disseminated or blood pressure; guaiac- Name: the first intravascular c In low doses, IV (Adults and use), rashes, positive stools). Notify Hemochron sign of oagulation) prevents the Children): 10100 urticaria. health care professional if o Prevention of conversion of units/mL (10 bleeding these occur prothrombin to units/mL for Hemat: Easy clotting in o Assess pt for evidence of thrombin by its infants <10 kg, BLEEDING, bruising. arterial and additional or increased heart surgery; effects on 100 units/mL for anemia, thrombosis. Symptoms will (In a low-dose factor Xa all others) thrombocytop depend on area of regimen) for Higher doses solution to fill enia (can involvement prevention neutralize heparin lock set occur up to o Monitor pt for of postoperati thrombin, to needle hub; several weeks hypersensitivity reactions ve deep venous preventing the replace after after (chills, fever, urticaria) thrombosis conversion of each use. discontinuatio o Observe injection sites for and pulmonary fibrinogen to n of therapy) hematomas, ecchymosis, or embolism in fibrin SC (Adults): inflammation patients Therapeutic 5000 units IV, o In pt. requiring long-term undergoing Effect(s): followed by anticoagulation, oral major Prevention of initial subcut anticoagulant therapy should abdomino- thrombus dose of 10,000 be instituted 45 days prior thoracic surge formation 20,000 units, to discontinuing heparin ry or who for Prevention of then 8000 therapy other reasons extension of 10,000 units q 8 o Advise pt to report any are at risk of existing hr or 15,000 symptoms of unusual developing thrombi (full 20,000 units q 12 bleeding or bruising to dose) hr. thromboemboli health care professional c disease immediately o Instruct pt not to take medications containing aspirin or NSAIDs while on heparin therapy o Caution pt to avoid IM injections and activities leading to injury and to use a soft toothbrush and electric razor during heparin therapy o Advise pt to inform health care professional of medication regimen prior to treatment or surgery ROMAMEA B. MAGDAYAO