Nothing Special   »   [go: up one dir, main page]
Scribd Logo
Upload

Welcome to Scribd!

  • 27 views

    Aan Sucitra H Fakultas Kedokteran Universitas Muhammadiyah Makassar

    Uploaded by

    muh ilyas
    Hyperuricemia is associated with an increased risk of major adverse cardiac events in patients with acute coronary syndrome. A study of patients hospitalized for acute coronary syndrome found that those with hyperuricemia had a 60% 7-day MACE-free survival rate, compared to 82% for those with normal uric acid levels. Patients with hyperuricemia also had MACE occur on average 1.25 days earlier during hospitalization. Hyperuricemia is an independent risk factor that can lead to increased risk of MACE in acute coronary syndrome patients.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    Aan Sucitra H Fakultas Kedokteran Universitas Muhammadiyah Makassar

    Uploaded by

    muh ilyas
    27 views7 pages
    Hyperuricemia is associated with an increased risk of major adverse cardiac events in patients with acute coronary syndrome. A study of patients hospitalized for acute coronary syndrome found that those with hyperuricemia had a 60% 7-day MACE-free survival rate, compared to 82% for those with normal uric acid levels. Patients with hyperuricemia also had MACE occur on average 1.25 days earlier during hospitalization. Hyperuricemia is an independent risk factor that can lead to increased risk of MACE in acute coronary syndrome patients.

    Original Description:

    PRESENTASI KASUS

    Original Title

    HiPeruRiseMia

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Hyperuricemia is associated with an increased risk of major adverse cardiac events in patients with acute coronary syndrome. A study of patients hospitalized for acute coronary syndrome found that those with hyperuricemia had a 60% 7-day MACE-free survival rate, compared to 82% for those with normal uric acid levels. Patients with hyperuricemia also had MACE occur on average 1.25 days earlier during hospitalization. Hyperuricemia is an independent risk factor that can lead to increased risk of MACE in acute coronary syndrome patients.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    27 views7 pages

    Aan Sucitra H Fakultas Kedokteran Universitas Muhammadiyah Makassar

    Uploaded by

    muh ilyas
    Hyperuricemia is associated with an increased risk of major adverse cardiac events in patients with acute coronary syndrome. A study of patients hospitalized for acute coronary syndrome found that those with hyperuricemia had a 60% 7-day MACE-free survival rate, compared to 82% for those with normal uric acid levels. Patients with hyperuricemia also had MACE occur on average 1.25 days earlier during hospitalization. Hyperuricemia is an independent risk factor that can lead to increased risk of MACE in acute coronary syndrome patients.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 7

    Aan Sucitra H

    Fakultas Kedokteran Universitas Muhammadiyah Makassar

    Introduction
    Coronary

    artery disease (CAD) is the leading


    cause of death in both western and developing
    countries such as Indonesia. Data from intensive
    cardiac care unit (ICCU) Cipto Mangunkusumo
    National General Hospital (RSUPNCM) in 20012005 showed that the cases of acute coronary
    syndrome (ACS) increases from year to year.

    In

    addition to the established risk factors of


    atherosclerosis, such as diabetes, hypertension, smoking
    and dyslipidemia, other factors such as hyperuricemia also
    have a signifiant role for the occurrence of CAD.

    The mortality rate of patients with acute myocardial

    infarction with high uric acid levels increased by 3.7 times


    compared to patients with normal uric acid levels.
    Hyperuricemia can lead to increase risk of major adverse

    cardiac events (MACE) in ACS patients due to free radical


    formation, platelet adhesiveness, and cardiomyocyte
    dysfunction and hyperptrophy.

    Metodhs
    Patients were excluded if they have diagnosis of heart

    failure, acute cerebrovascular accident (CVA) or stroke,


    cardiogenic shock, as well as died in the fist day of
    admission based on medical record data.

    RESULTS

    Kaplan-Meier survival curve (Figure 1) showed there was signifiant difference of 7-days
    MACE-free survival between hyperuricemic and normouricemic groups; 60% vs. 82%,
    respectively (p log-rank <0.001)

    DISCUSSION
    Patients with hyperuricemia having more than 20%

    lower of MACE-free survival compared to


    normouremic patients, and in average the MACE were
    occurred 1.25 days earlier during hospitalization in
    hyperurisemic patients.

    CONCLUSION
    There was MACE-free survival difference between

    hyperuricamic and normouricemic patients and


    hyperuricemia is a risk factor for major adverse cardiac
    events (MACE) in hospitalized acute coronary syndrome
    patients

    You might also like